16 



C. L. SADRON 



Fig. 6. DNA double helix. 



law of sequence of the A-T and C-G groups along a particle of DNA of i 

 given chemical composition, here we shall limit ourselves to the descriptioi 

 of its morphological characters, such as weight and configurations. 10 



1. The Effect of Inter- and Intramolecular 

 Interactions: Rigidity of DNA Particles 



a. Iniermolecular Interactions 



First, let us recall that the general methods of analysis of the intrinsi 

 characters of macromolecules in solution are based upon the assumptioi 



10 Reviews on the same subject have already been given by different authors, fo 

 instance, 



(a) P. Doty, Proc. 3rd Intern. Congr. Biochem., Brussels, 1955 p. 135 (1956). 



(b) C. Sadron, Proc. 3rd Intern. Congr. Biochem., Brussels, 1955 p. 125 (1956). 



(c) C. Sadron and J. Pouyet, Proc. 4th Intern. Congr. Biochem., Vienna 1958 p. 5: 

 (1959). 



Special mention is to be made of more extensive papers, such as, 



(d) K. V. Shooter, Progr. in Biophys. 8, 310 (1957). 



(e) J. Hermans, Jr., Thesis, Leiden (1958). 



