SUBJECT INDEX 



585 



primers for, 127-129 

 size of polymers, 126-127 

 structure t)f polymers, 126-127 



Ribosomes 

 aggregation of, 357-358 

 amino acid composition, 359 

 amino acid incorporation and, 426-427 

 enzymatic properties, 362-363 

 extraction of, 357 

 macromolecular organization, 361 

 metabolic origin, 371 

 morphology of, 353-355 

 physical properties of, 357 

 protein synthesis and, 363-371 

 ribonucleic acid of, 358, 360 

 size distribution, 354, 356-357 

 stabilization of, 357 

 subunits of, 355-358 



5-Ribosyluracil 



ribonucleic acids and, 159 

 soluble ribonucleic acid and, 375 



S 4 fraction, soluble ribonucleic acid and, 



391 

 Sarcoma-180, 473, 478, 485 

 Serine, incorporation of, 338 

 Shape, molecular, see Molecular shape 

 Small intestine, radiation effects, 534-535 

 Spleen, radiation effects, 535-536, 539 

 Soluble ribonucleic acid 



adenine moiety and, 390 



amino acid acceptors and, 384 



amino acid activation and, 383 



amino acid attachment 

 requirements for, 385 

 site of, 385-386 

 terminal groups for, 384-385 



bacterial cells and, 412-416 



base composition, 374-375 



heterogeneity of, 375-376 



molecular weight, 374 



occurrence, 372-374 



preparation, methods, 372-374 



S 4 fraction and, 391 



Tetraethylthiuramdisulfide, 461 

 Tetrohydrofolic acid 

 coenzyme action of, 459 



derivatives of, 312-313, 459-460 

 metabolism, 457, 460-462 

 Thioghunine 



azaserine pretreatment, effect of, 485- 



486 

 clinical use of, 484-485 

 mechanism of action, 485-487 

 microbial studies and, 486-487 

 structure of, 478 

 Thioguanosine-5'-phosphate, 485 

 2-Thiouracil 



biological activity of, 517-519 

 tobacco mosaic virus and, 276-277 

 Thymidine-H 3 , 531-532 

 Thymidine kinase, 542 

 Thymidine oligonucleotides 



cyclic polymer synthesis, 121-122 

 linear polymer synthesis, 120-122 

 Thymidine-5'-phosphate 

 biosynthesis of 



cell-free systems, 342-346 

 methylation reactions, 344-345 

 preformed thymine derivatives and, 



346-347 

 whole cell systems, 337-342, 461 

 polymerization of 



3'-0-acetylthymidine-5'-phosphate 



and, 121-122 

 problems of, 121 

 Thymidine-3'-phosphate, polymeriza- 

 tion of, 122 

 Thymidine phosphorylase, 509 

 Thymidine, utilization of, 347 

 Thymidilate synthetase, 342-343, 345 



inhibition of, 504 

 Thymidylic acid 



dihydro folic acid reductase, 461 

 synthesis of, 460-461 

 Thymidylic kinase, 542 

 Thymidylic synthetase, 214 

 Thymidylyl-5'-thymidine, synthesis of. 



110, 111 

 Thymine 



antagonists of, 511-512 

 phage synthesis and, 231, 232 

 photolysis and, 76 

 ribonucleic acid and, 160 

 ultraviolet irradiation and, 100 

 Thymineless death, 498, 503, 507, 516 



