SUBJECT INDEX 



577 



pyrimidine origin, 212 



ribose nucleic acid as precursor, 214- 



216 

 synthesis, time course, 205-208 

 ultraviolet irradiation and, 196-200, 

 227 



genetic loci and, 218-221 

 Deoxyribonucleic acid-thymidine, pre- 

 cursors of, 337-340, 345 

 Deoxyribonucleic acid, T-odd phage 



and, composition of, 229, 231 

 Deoxyribonucleoside-5'-phosphates, pol- 

 ymerization of, 122-123 

 Deoxyribonucleotide kinases, 213 

 Deoxyribo-oligonucleotides 

 polymerization of, 122-123 

 synthesis of, 113-117 

 Deoxyribopolynucleotides 

 enzymic synthesis of, 



analog incorporation, 140 

 carcinoma and, 146 

 enzymes of, 137-138 

 liver and, 145 

 mechanisms of, 143-145 

 microorganisms and, 136-145 

 phage-infected cells and, 141-143 

 precursors of, 136 

 pyrophosphate and, 138-139 

 reaction primer, 139-140, 144 

 thymus and, 145-146 

 Deoxyuridine, methylation of, 343-344 

 Diaminodihydrotriazine, 469-471 

 mechanism of action and, 471 

 resistance to, 471 

 structure of, 469 

 sulfadiazine and, 470-471 

 Diaminopurine 

 mechanism of action and, 493-495 

 metabolism of, 494 

 resistance to and, 495 

 Diaminopyrimidine, 469-471 

 mechanism of action and, 471 

 resistance to, 471 

 structure of, 469 

 O-Diazoacetyl-L-serine, see Azaserine 

 6-Diazo-5-oxonorleucine, enzyme inhibi- 

 tion and, 313-314 

 6-Diazo-5-oxo-i.-norleucine 

 antagonists of, 476 

 leukemia and, 477 



mechanism of, 473-477 



pyrimidine nucleotides and, 334 



structure of, 473 

 Dicyclohexylcarbodiimide, phosphodi- 



ester bonds and, 112-113 

 Dihydrodeoxycytidine, ultraviolet ab- 

 sorption of, 53 

 Dihydrodimethyluracil, absorption max- 

 imum, 54 

 Dihydrofolic acid reductase 



amethopterin and, 458 



thymidylic acid and, 4(il 

 Dihydrooratase, 327 

 Dihydroorotic acid dehydrogenase, 327 

 Dihydropyrimidine derivatives, ultra- 

 violet absorption of, 52-54 

 Dihydrouracil 



nucleotide synthesis and, 347-348 



ultraviolet absorption of, 53-54 

 Dimethyluracil 



photoproducts of, 72 



reversible photolysis, 70-72 

 Diphosphopyridine nucleotide, ultra- 

 violet irradiation and, 66-68 

 DON, see 6-Diazo-5-oxo-norleueine 



E 



E. colt 



base analogs and, 433-436 

 deoxyribonucleic acid synthesis in, 



436-437 

 enzyme induction and, 431-435 

 nucleic acid synthesis and, 436-438 

 protein synthesis in, 419-421, 423-426, 



430-436 

 ribonucleic acid synthesis in, 422, 427, 



429, 430-432, 436, 438 

 ribonucleoprotein, state of, 415-417 

 soluble ribonucleic acid of, 413-416 

 unbalanced growth and, 431 

 Einstein unit, 41 

 Electron spin resonance, 44-45 

 Endoplasmic reticulum, membrane of, 



354-355 

 Energy transfer, 92-93 

 Enzyme induction, 142-143, 431-435 

 Ervthrochloramphenicol, nucleic acids 



and, 523 

 Ethidium bromide, nucleic acids and, 523 

 2-Ethoxyuracil, photolysis and, 76 



