582 



SUBJECT INDEX 



requirements for, 77-78 



solvent effects, 78-79 



uracil analogs and, 69-73 

 Photoreactivation, 88-90, 96-99 



bacteriophage and, 192 



features of, 97 



mechanism of, 89, 97-99 



model studies and, 97-98 

 Polyadenylic acids, ultraviolet absorp- 

 tion of, 55, 56 

 Polycytidylic acid, hyperchromicity of, 



56 

 Polyinosinic acid, ultraviolet absorption 



of, 55, 56 

 Polymerase 



deoxyadenylic-thymidylic polymer 

 and, 141 



enzyme induction and, 143 



rat tissue and, 146 



reactions of, 137-138, 144 



requirements for, 137 



thymidine oligonucleotides as prim- 

 ers, 144-145 

 Polynucleotide phosphorylase, 



co-factors and, 125 



deoxyribonucleic acid synthesis and, 

 509 



distribution of, 132 



guanosine-5'-diphosphate and, 131-132 



inhbition of, 515 



kinetics, 125-126 



mechanism of action, 130-132 



oligonucleotides as primers, 128-129 



oligoribonucleotides prepared by, 133 



polynucleotides as primers, 127-128 



polyribonucleotides prepared by, 133 



primer specificity and, 128 



reactions catalyzed, 131 



ribonucleoside-5'-diphosphate and, 124 



source of, 124-125 



specificity of, 125-126 



structure and size of products, 126-127 

 Polynucleotides 



chemical synthesis of, 108-124 



enzymic primers and, 127-128 



hyperchromicity of, 54-59 



nomenclature of, 105-108 



abbreviated formulations, 105-106 

 diagrammatic representations, 106- 

 108 



phosphorolysis of, 129-130 



synthesis of, 124-146 

 Polyribonucleotides, polynucleotide 



phosphorylase and, 133 

 Polyribothymidylic acid, 100-101 

 Polyuridylic acid, ultraviolet absorption 



of, 55-56 

 Polyvinylbutylpyridium bromide, 18-19 

 Proflavine, mutagensis and, 223-225 

 Prophage, nature of, 236, 239-240 

 Proteins 



far ultraviolet spectra, 51 



metabolic stability of, 419-421 



ultraviolet irradiation and, 80-81 

 Protein synthesis 



"Adapter hypothesis" and, 401-406 



adenosine triphosphate and, 388-389, 

 392 



amino acid analogs and, 406 



amino acid sequence and, 399, 401 



cell membranes, bacterial, and, 396- 

 398 



chloroplasts and, 395 



criteria of, 351 



definition of terms, 351 



deoxyribonucleic acid and, 399-400, 

 407-408 



endergonic nature of, 365-366 



endoplasmic reticulum and, 368 



genetic coding and, 399-400 



guanosine triphosphate and, 388-392 



inhibition of, 492 



mechanism, theoretical, 398-408 



membrane component and, 378 



microorganisms and, 367 



microsomes and, 388, 390 



mitochondria and, 395 



nuclei and, 396 



reactions of, 363-364 



ribonucleic acids and, 152-155, 398-407 



ribosomes and, 352-371, 388-390 



site of, 352, 366 



"S-protein" and, 393-394 



template mechanism and, 399, 403 



transfer ribonucleic acid 

 soluble systems and, 371-372, 388-394 

 whole cells and, 386-388 

 Protein synthesis, in vivo 



amino acid incorporation 



intracellular pool and, 423-426, 447 



