SUBJECT INDEX 



583 



ribonucleic acid and, 423-426, 447 



450 

 ribosomes and, 426-427 

 soluble protein and, 426-427 

 soluble ribonucleic acid and, 423- 

 426, 447-448 



base analogs and, 433-436 



cell membrane and, 427-428 



deoxyribonucleic acid and, 448-449 



deoxyribonucleic acid synthesis ab- 

 sent, 430-432 



enucleation and, 440-442 



intermediate steps in, 447-448 



protein forming system and, 448-449 



regulation of, 449-450, 



ribonucleic acid content and, 442-446 



ribonucleic acid synthesis absent, 432- 

 436 



site of, 427-428, 447-450 



template and, 449 

 Protozoa, ribonucleic acid composition 



of, 180 

 Purine, analogs of 



azaguanine, 487-493 



diaminopurine, 493-495 



6-mercaptopurine, 477-484 



nebularine, 497 



puromycin, 496 



pyrazalopyrimidines, 496 



thioguanine, 484^87 

 Purine nucleotides, biosynthesis of 



formyltetrahydrofolic acid compounds 

 and, 318-319 



inosinic acid and, 306-317, 319-322 



purine precursors and, 304-306 

 Purines 



amination in synthesis of, 471-478 



glutamine, in synthesis of, 471-478 



incorporation of formate, 482 



incorporation of glycine and, 482 



structural analogs of 477-497 

 Purines, precursors of, 304-306 



carbon atoms of, 304-305 



formate and, 305-306 



glycine and, 305-306 



ribose phosphate and, 306 

 Pycnometry, 4 

 Pyrimidine nucleosides 



infrared spectroscopy, 51 



photochemistry of, 68-79 

 Pyrimidine nucleotides 



biosynthesis of, 323-348 



alternate pathways, 347-348 

 cytidine nucleotides and, 332-337 

 thymidine nucleotides and, 337-347 

 uridine nucleotides and, 323-332 



photochemistry of, 68-79 



photoreactivation of, 98-99 

 Pyrimidines 



amination in synthesis of, 471-478 



analogs of, 



azapyrimidines, 512-516 

 fluorocytidine, 506 

 5-fluorocytosine, 506 

 5-fluorouracil, 498-506 

 5-fluoroorotic acid, 498-506 



glutamine, in synthesis of, 471-478 



X-ray irradiation and, 101-102 

 Pyrophosphorylase, 481, 496 



Quinones, 43-44 



Racker aldolase, 341 

 Radiation 



biological effect, 527 



chromosome damage and, 528 



deoxyribonucleic acid synthesis and, 

 528-533, 536, 538, 540-546 



effects of 



biochemical milieu and, 539 

 bone marrow, 535, 539-540 

 glycine incorporation and, 533 

 indirect effects, 536-537 

 intranuclear phosphorylation, 543 

 mechanism and, 545-546 

 oxygen tension and, 538-539 

 P 32 incorporation and, 533, 534 

 precursor pools and, 540-541 

 Regenerating liver, 537-538 

 small intestines, 534-535 

 spleen and, 535-536, 539 

 thymus and, 535-536, 539 

 tumors and, 532-534 



enzyme liberation and, 531 



nucleic acid metabolism and, 527-546 



receptors of, 90-93 



