Subject Index 



Actinometry, chemical, 48-49 



malachite green leucocyanide acinom- 



eter, 49 

 uranyl oxalate actinometer, 48-49 

 Action spectrum, 90-93 

 deoxyribonucleic acid films and, 90-91 

 nucleic acids and, "91 

 proteins and, 91-92 

 tobacco mosaic virus and, 91 

 Adenines, ultraviolet irradiation and, 



63-64 

 Adenine nucleotides, transfer ribonucleic 



acid and, 377-378 

 Adenosine deaminase, inhibition of, 491 

 Adenosine diphosphate, ultraviolet ir- 

 radiation and, 66-67 

 Adenosine monophosphate, transfer ri- 

 bonucleic acid and, 377-380 

 Adenosine triphosphate 

 amino acid activation and, 380-384 

 amino acid attachment and, 385-386 

 protein synthesis and, 351, 364, 367- 



369, 388-389, 391, 392 

 purine synthesis and, 307-309 

 ribonucleic acid and, 134-135 

 ultraviolet irradiation and, 61, 63, 66, 

 67 

 Adenylate kinase, 331-333 

 Adenylic acid 

 biosynthesis of, 308 

 enzymes of, 320 

 guanosine compounds and, 320 

 inosinic acid and, 319-320 

 ultraviolet destruction of, 62 

 Adenylsuccinase, 320 

 Adenylyl-5'-uridine, synthesis of, 110, 



111', 117-118 

 /3- Alanine, pyrimidine synthesis and, 348 

 Algae 



ribonucleic acids of, 180 

 deoxyribonucleic acids of, 174-175 

 Allantoin, 66 



Amethopterin 



antibodies and, 467-468 



bacterial resistance and, 466 



blood-brain barrier and, 468-469 



clinical studies, 465 



dependent leukemia strain, 466-468 



drug resistance to, 465-466 



halogenated derivatives of, 464-465 



leukemia and, 457, 463-464 



ljonphocytic choriomeningitis virus 

 and, 467 



pharmacology of, 468-469 



sarcoma and, 180, 461 



sensitive tissues, 461 



structure, 456 



thymidylic acid formation, 460 



toxicity, 459 

 Animation reactions, nucleic acids and 



471-475 

 Amino acid activation 



amino acid analogs and, 447 



bacterial cells and, 412-416 



enzymes of, 380-384 



mechanism of, 381-384 

 Amino acid activating enzymes, 412-413 

 5-Aminoimidazole ribonucleotide 



biosynthesis of, 314 



isolation and properties, 314 

 5-Aminoimidazole ribonucleotide car- 

 boxylase, 315 

 5-Amino--4-imidazolecarboxylic acid ri- 

 bonucleotide 



biosynthesis of, 314-315 

 5- Amino -4 -imidazole -N-succinocarbox- 

 amide ribonucleotide, biosynthesis 

 of, 315-316 

 Aminopterin 



enzyme inhibition, 458-459 



leukemia, 457 



structure, 456 



toxicity, 459 

 2-Aminopurine, mutagensis and, 223-225 

 5-Aminopyrimidine, 511 



573 



