796 



7. MERCURIALS 



3- 



Fig. 7-15. Effects of pH on the ^„ and V„ for ^-glucuronidase, 

 and the K, for the inhibition by p-MB. (From Fernley, 1962.) 



standing of the mechanisms of enzyme inhibition. The pH changes may af- 

 fect the reactivities of different SH groups on an enzyme to different de- 

 grees. Xanthine oxidase has two types of SH group, one reacting relatively 



100 



80 



40 



20 



CU (0 63mM| 

 PM(025mM) 



Fig. 7-16. Effects of substrate concentration 



on the inhibition of /3-glucuronidase by 



p-MB, PM, and Cu++ at pH 5.9. (From 



Fernley, 1962.) 



