SUBJECT INDEX 



1217 



NAD nucleosidase, 489, 491 



structure of, 488 

 PjTimethamine (Daraprim), 



folate deficiency, 584 



folinate formation, 584 



uptake by bacteria, 584 

 Pyrimidines, metabolism of, 



fluoropyrimidines, 478-481 

 Pyrithiaminase, 528-529 

 Pyrithiamine (neopyrithiamine), 



bacterial growth, 528-530 



bacterial resistance to, 528-529 



blood pyruvate, 520, 527 



central nervous system, 527, 530 



fungal growth, 516, 528-529 



glutamate metabolism in seeds, 522 



heart rate in vivo, 527 



miosis, 532 



nerve membrane potentials, 531 



neuromuscular block, 531-532 



phosphorylation of, 519, 527 



pyruvate decarboxylase in vivo, 531 



pyruvate dismutation in vivo, 521 



pyruvate oxidation in vivo, 520-521 



rat growth, 527 



respiratory quotient in rats, 521-522 



structure of, 517 



thiaminase, 523-524 



thiamine deficiency, 516, 530-532 



thiamine kinase, 522-523 



thiamine levels in tissues, 525-527 



thiamine-PP levels in tissues, 521 



tissue levels of, 527-528 



toxicity, 530-531 



Vibrio growth, 530 

 Pyrithiamine-diphosphate, 



pyruvate decarboxylase, 518 



pjTuvate oxidase, 519 

 Pyrocatechase, mercurials, 853 

 PjTOgallol, 



adrenergic potentiation, 611 



D-amino acid oxidase, 344 



blood pressure, 611 



catecholamine metabolism, 611-612 



catechol-0-methyl transferase, 595, 611- 



612 



dehydroshikimate reductase, 593 



epinephrine responses, 611 



histidine decarboxylase, 352 

 norepinephrine level in brain, 611 

 urinary catecholamines, 611-612 

 Pyrophosphatase, 



o-iodosobenzoate, 712 

 malonate, 64 



mercurials, relation to SH groups, 802 

 nucleotides, 475 

 phosphate, 439 

 P>Tophosphate, 



glutamate semialdehyde reductase, 507 

 ionization constants, 242 

 NAD nucleosidase, 492 

 oxidative phosphorylation, 448 

 phosphatases, 439 

 pyridoxal kinase, 477 

 succinate dehydrogenase, 243 

 tyrosinase, 301 

 Pyrophosphite, oxidative phosphoryla- 

 tion, 448 

 Pyrrole-2-carboxylate, D-amino acid oxi- 

 dase, 342, 346 

 A 1 - Pyrroline - 5 - carboxylate dehydroge- 

 nase, analogs, 336, 355 

 A 1 - Pyrroline - 5 - carboxylate reductase, 



analogs, 355 

 a-Pyrrone-5-carboxylate, see Coumalate 

 Pyruvate, 



accumulation of, ferricyanide, 677 

 D-amino acid oxidase, 340 

 blood levels of, 



malonate, 219 



thiamine analogs, 520, 527 

 decarboxylation of, 



2-deoxyglucose, 396 



lipoate analogs, 590 

 dismutation of, pyrithiamine, 521 

 glycerate dehydrogenase, 430 

 glyoxylate reductase, 438 

 lactate dehydrogenase, 437 

 malate dehydrogenase, 596 

 oxidation of, 



acetylene-dicarboxylate, 240-241 



analogs, 429-432 



benzoate, 349 



trans - cyclopentane -1,2- dicarboxy- 



late, 241 



2-deoxyglucose, 391-392, 397, 399 



