AXTIHEPTICS 



129 



imal inhibiting dose of a compound, it is necessary also 

 to study the complete multiplication curve as atfected 

 by sub-minimal doses, to measure the length of the lag 

 period, the multiplication rate and the final *'crop." No 

 such complete data for any particular compound could 

 be found in the literature. For the data of Table 25, the 

 author is indebted to Miss Jean E. Conn, of the Agri- 

 cultural Experiment Station, Geneva, N. Y. They are 

 part of a comprehensive study to determine the effect 

 of acidity on various antiseptics. 



It should be pointed out first that the two compounds 

 which are mentioned in this table and which will be 

 considered here, formaldehyde and phenol, were hardly 

 affected by acidity. With formaldehyde there was no 

 influence whatever; at all acidities included in the test. 



TABLE 25 



Multiplication of Saccharomyces ellipsoideus in presence of phenol 

 and formaldehyde. (Unpublished data by Jean E. Conn.) 



