66 METABOLISM IN CHANGED CEREBRAL ACTIVITY 



brain (Florsheim and Morton, 1954) though no indication was 

 given of the extent of any tissue damage. 



Ahhough studies of the effects of thiamine deficiency upon 

 cerebral metabohsm are numerous, few relate to phosphate 

 metabolism. Boldyreva (1940) reported that levels of both cerebral 

 phosphocreatine and inorganic phosphate were increased while 

 those of adenosine triphosphate decreased in aneurin deficient 

 pigeons. Brante (1949) found that thiamine deficiency, like panto- 

 thenic acid or choline deficiency, had no effect upon the synthesis 

 of the total phospholipids of rat brain during the period of growth. 



References 



Abood, L. G. and Geiger, A. (1955) Amer.J. Physiol 182, 557. 

 Albaum, H. G., Noel, W. K. and Chinn, H. I. (1953) Amer.J. Physiol. 



174, 408. 

 Albaum, H. G., Tepperman, J. and Bodansky, O. (1946) J. biol. chem. 



164, 45. 

 Albert, S. and Leblond, C. P. C. (1946) Endocrinol. 39, 386. 

 Anderson, J. A., Gemzell, C, Gemzell, L. L., Bolin, V. S. and 



Samuels, L. T. (1950) Proc. soc. exp. biol. N.Y. 73, 690. 

 Ansell, G. B. and Dohman, H. (1956) J. Nenrochem. 1, 150. 

 Ansell, G. B. and Dohman, H. (1957) J. Neurochem. 2, 1. 

 Bain, J. A. (1957) in Progress in Neurobiology, Vol. II, p. 139 (Ed. by H. 



Waelsch), Hoeber, New York. 

 Bain, J. A. and Klein, J. R. (1949) Amer. J. Physiol. 158, 478. 

 Bain, J. A., Pollock, J. H. and Stein, S. N. (1949) Proc. soc. exp. biol. 



N.Y. 71, 497. 

 Bakay, L. (1953) Arch. Neurol. Psychiat. Chicago 70, 30. 

 Bakay, L. (1955) Arch. Neurol. Psychiat. Chicago 73, 2. 

 BoiviN, A., Vendrely, R. and Vendrely, C. (1948) C.R. Acad. Sci., Paris 



226, 1061. 

 Borell, U. and Ostrom, A. (1947) Biochem. J. 47, 398. 

 Britton, S. W. and Kline, R. F. (1945) Amer. J. Physiol. 145, 190. 

 Brante, G. (1949) Acta, physiol. scand. 18, Suppl. 63. 

 Burton, R. M. (1957) J. Neurochem. 2, 15. 

 Boldyreva, N. V. (1940) J^. Physiol. U.S.S.R. 29, 582 (Chem. Abstr. 36, 



6215). 

 Chaikoff, I. L., Changus, G. W. and Ruben, S. (1938) J. biol. chem. 126, 



493. 

 CiCARDO, V. H. (1945) Amer. J. Physiol. 145, 542. 

 Grain, S. M. (1952) Proc. soc. exp. biol. N.Y. 81, 49. 

 Cremer, J. E. (1957) Biochem. J. 67, 87. 

 Davies, p. W. and R^mond, A. (1947) Res. pub. assoc. nerv. ment. dis. 21, 



205. 



