10 METABOLISM IN THE NORMAL FUNCTIONAL STATE 



reactions in which these and other nucleotides participate is 

 deferred to later chapters. 



The quantities of phosphorylated intermediates of the glycolytic 

 pathway are given in Table 3. With few exceptions there is 



Table 3. — Quantities of Phosphorylated Intermediates of 

 Glucose in Brain in vivo 



Superscripts denote author references 



(1) Rat; Abood et al. (1952). (2) Rat; Albaum et al. (1946). (3) Rat; Le 

 Page (1946). (^^ Rat; Dawson and Richter (1950«). (^^ Guinea pig; 

 Kratzing and Narayanaswami (1953). (^^ Guinea pig; Heald (1956a). 

 (')Cat; Klein and Olsen (1947). («> Dog; Stone (1943). (»> Rabbit; 

 Thorn et al (1955). d^^ Rabbit; Thorn, et al. (1958). ("^ Rat; Vladi- 

 mirov and Rubel (1957) (assuming 3 g wt. of brain), d^) Rat; Paladini 

 (1951). 



reasonable agreement between the results of various workers. As 

 with the nucleotides, values are given for brains frozen in vivo and 

 differences may be ascribed either to analytical methods or to 

 treatment of the brain after freezing. Here also, quantities 

 estimated by specific enzymic methods (Kratzing and Narayana- 

 swami, 1953; Thorn et al, 1955, 1958) are preferred to those 

 obtained by other techniques. It is of interest that the quantity of 



