186 



SUBJECT INDEX 



Adenosine phosphates 

 Adenosine triphosphate — 

 continued 

 ^'P incorporation into during 

 during electrical stimulus, 

 116, 117 

 ^^P incorporation into a-phos- 



phorus of in vitro, 84 

 identification of in brain, 1 1 

 in the formation of inosine 



monophosphate, 8 

 quantities of in brain in vivo, 

 6,7 

 effects of anaesthesia on, 44, 



45 

 effects of removing brain 



and convulsions, 55-60 

 during development, 37 

 in hypoglycemia, 48 

 in anoxia, 50, 51 

 in hypothermia, 51 

 in ischaemia, 53 

 in conditioned response, 62 

 following brain injury, 64 

 in virus infection, 64 

 in brain after poisoning 

 with trialkyl tin com- 

 pounds and dinitro-o- 

 cresol, 64, 65 

 in brain of thiamine de- 

 ficient animals, 66 

 quantities of in cortical slices 

 in vitro, 78, 79 

 metabolic inhibitors on, 107, 



108 

 electrical stimulus on, 114, 



115 

 barbiturates on, 141, 147 

 requirement for in the syn- 

 thesis of phospholipids, 89, 

 90 

 role in changes following elec- 

 trical stimulus of brain, 119, 

 120 

 role in synthesis of guanine 

 nucleotides in vitro, 80 

 Adenosine triphosphatase 



Activity in cell dispersions, 86, 1 23 



Activation by depressants, 144 



Activation by heavy metals, 127 



Latent, in mitochondria, 82 



Increase in activity during de- 

 velopment, 38 



Inhibition by fluoride, 82 

 Ammonium sulphate 



As extractant for labile phos- 

 phates, 163 

 Amobarbitone 



Anaesthetic concentration in 

 brain, 139 



Effects upon oxidative phospho- 

 rylation by brain mitochon- 

 dria, 142 

 Anaesthesia 



Carbohydrate metabolism 

 during, 44 



Acid-soluble phosphates of brain 

 during, 44—47 

 Analytical methods (see also 

 individual phosphates) 



for phosphate derivatives in 

 brain, 161-176 

 Anoxia 



Changes in phosphocreatine, 

 adenosine triphosphate and 

 inorganic phosphate during, 

 49-51 



effect on phosphocreatine syn- 

 thesis in slices, 103-104 



Lactic acid in brain during, 49, 51 



Oxygen consumption in brain 

 during, 49 

 Azide 



Effects upon phosphates in vitro, 

 107, 108 



Barbitone 



Anaesthetic concentration in 

 brain, 139 

 Barbiturates 



Anaesthetic concentrations in 



brain, 139 

 Effects of, on levels of phos- 

 phates in vivo, 44, 45 

 on ^^P metabolism in adeno- 

 sine triphosphate, 46 



