190 



SUBJECT INDEX 



Inorganic phosphate — continued 

 Changes in cerebral slices, in 

 electrically stimulated tis- 

 sue, 110-114 

 with increased potassium salts, 



179-180 

 speed of changes, 115 

 Loss from slices during incu- 

 bation, 79 

 Necessity for in oxidation of 



substrates, 81 

 Radioactive phosphate, acclima- 

 tization to high altitudes on 

 turnover of, 30 

 as standard for computing 



metabolic rates, 22 

 limitations to use as stan- 

 dard, 155 

 entry into brain in vivo, 15-17 



metabolic processes in, 15 

 entry into slices in saline, 80 

 incorporation into adenosine 



triphosphate in vivo, 19 

 incorporation into phospho- 

 lipids in vitro, 88-91 

 retention of by brain, 44 

 transport from cerebrospinal 



fluid to brain, 18 

 unequal penetration into areas 



of brain, 18, 21 

 vascularity and entry to brain 

 areas, 19 

 Quantities of in brain in vivo, 6, 7 

 in brain slices, 78, 79 

 Inosine phosphates 



Monophosphate, quantities in 

 brain in vivo, 9 

 formation from adenosine 

 monophosphate, 8 

 Diphosphate, quantities in brain 



in vivo, 9 

 Triphosphate, phosphorylation 

 of adenosine triphosphate 

 by, 122-123 

 quantities in brain in vivo, 9 

 Inositol phospholipids (see also 

 Cephalin diphosphoinos- 

 itide) 



In phosphatido-peptides, 14 

 In " residual organic phos- 

 phates ",14 

 Quantities in brain, 13 

 Injury 



Effects on phosphate metabolism, 

 63-64 

 Intracisternal injection 



In studies with ^^P in vivo, 19 



lODOACETIC ACID 



Effect on phosphate metabolism 

 in vitro, 107-108 

 Ischaemia (cerebral) 



Effect on phosphate levels, 52-53 



Lecithins (see also Phosphatidyl 

 choline) 



Cytidine triphosphate in syn- 

 thesis of, 9, 90 



Hydrolysis of by brain prepara- 

 tions, 92 



Synthesis of in vitro, 90-91 



Quantities of in vivo, 1 3 

 Liquid nitrogen 



As coolant for freezing brain 

 before analysis, 161-163 



Malonate 



Effect on phosphate metabolism 

 in vitro, 107-108 

 Metabolic inhibitors 



Effects on quantities and ^^P 

 metabolism of phosphates in 

 vitro, 107-109 

 Metrazole 



Changes in phosphates during 

 convulsions induced by, 55 

 Mitochondria 



Characteristics of brain prepara- 

 tions, 75-77 

 Myelination 



Increase in acid-soluble phos- 

 phates during, 37 

 Increase in phospholipids during, 



39,41 

 Physiological stages in, 35 

 Retention of ^^P in phospholi- 

 pids during, 41-42 



