116 BIOLOGY OF PNEUMOCOCCUS 



The occurrence of many of these pneumococcal types in Ger- 

 many has been reported by Silberstein (1933), 1287 who found 

 twenty-one of the new types, while there were only three strains 

 which could not be classified. Types XVI, XXI, XXIII, XXVIII, 

 XXX, and XXXII which had not before been reported in Ger- 

 many were among those identified by Silberstein. Of all the types, 

 XVIII and XIX seemed to be among the more common, as had 

 earlier been noted by Gundel and Schwartz.* 



That there may possibly be types beyond the present serological 

 classification is suggested by the report of Christie (1934). 231 Of 

 one hundred Group IV strains tested, forty-seven failed to react 

 with specific serum for any of the thirty-two known types. Nine- 

 teen of thirty-six cultures from healthy persons, sixteen of thirty- 

 six strains obtained from convalescent carriers, and twelve of 

 twenty-eight organisms isolated from patients with acute pneumo- 

 coccal pneumonia could not be identified by Christie with any of 

 the type-specific serums. In India, Napier and Dharmonda 943 en- 

 countered among the pneumococci isolated from forty-five cases of 

 lobar pneumonia and from fifteen cases of bronchopneumonia, 

 strains that failed to correspond to any of the recognized types. 

 Forty-six per cent of the strains studied apparently belonged to 

 two types found only locally. 



Recently two strains of pneumococci were described by Smith 1296 

 which the author claims constitute two new serological types. The 

 organisms were isolated on separate occasions from the respira- 

 tory tract of a man suffering from "chronic bronchitis." A third 

 but similar strain was found to be present in pure culture in the 

 lungs of an individual dying of pneumonia. The strains grew ana- 

 erobically and were virulent for mice but, under the conditions 

 tested, were not infectious to guinea pigs. The three strains ap- 

 peared to represent two distinct serological varieties both of which 

 differed from the thirty-two known types. There was no cross- 



* Quoted by Silberstein. 



