CHEMOTHERAPY 521 



cus may render the bacteria more vulnerable to the natural defen- 

 sive forces of the body, and this action may be a distinct aid in 

 specific serum therapy. Failure so far to discover a satisfactory 

 medicinal agent with pneumococcidal properties and free of unde- 

 sirable side effects is tempered with the promise offered by cin- 

 chona compounds and leaves this inviting and profitable field open 

 to renewed and extended investigation. 



Note : The introduction of the sulfonamide derivatives (sulfanilamide 

 and more especially sulfapyridine and sulfathiazole) has completely 

 altered the aspect of chemotherapy. The very general use of these 

 drugs and their recognized effectiveness need only be mentioned to 

 establish this point. 



E. S. R. 



L. A. B. 

 March, 1941 



