778 



INDEX 



Chemotherapy (cont.): 



cinchona derivatives, 512-520 



action, adjuvant, with specific 

 serum, 518-519 



action, toxic, of some drugs, 517 



alpha-isoquin'me, 516 



apocupreine hydrochloride, 517 



6e£a-isoquinine, 516 



dermal pneumonia in rabbits, 516 



effect on virulence of Pneumo- 

 coccus, 519-520 



ethylapoquinine, 516, 517 



ethylhydrocupreine. See Optochin 



hydroethylapoquinine, 516 



hydroquinine derivatives, 513 



hydroxyethylhydrocupreine, 516, 

 517 



isopropylhydrocupreine, 512 



methylhydrocupreine, 512 



optochin. See Optochin 



pneumococcidal potency of opto- 

 chin compared to antipneumo- 

 coccic serum, 512, 515, 519 



quinine, 512, 515 

 hydrochloride, 516 

 sulfate, 519 

 coal-tar dyes, 509-510 



acriflavine, 509 



application, 510 



aurophosphines, 510 



brilliant green, 510 



crystal violet, 510 



3-6 diamino-acridine, 510 



flavines, 509 



Mercurochrome, 510 



trimethanes, 510 



triphenylmethanes, 509 



trypaflavine, 510 

 drug-fastness of Pneumococcus, 



519-520 

 drugs, susceptibility of Pneumo- 

 coccus, 520 

 medicinal agents, various, 511 



camphor, 511 



epinephrine, 511 



formaldehyde sulfoxylate, 511 



hexamethyltetramine, 511 



Chemotherapy (cont.): 

 medicinal agents (cont.) : 

 potassium permanganate, 511 

 sodium salicylate, 511 

 Urotropin, 511 

 metals and metallic salts, 510-511 

 colloidal gold, 510 

 gold as synergist, 510 

 iodine, 511 

 Sanocrysin, 510 

 Metaphen, 510 

 soaps, 509 



lauric acid, 509 



sodium oleate, adjuvant action of, 



on immune serum, 509 

 sodium ricinoleate, 509 

 unsolved problems, 618 

 urea hydrochloride, 516 

 vuzine, 512, 515 

 Chill-producing factors in antipneu- 

 mococcic serum, 559-563 

 acid fraction, 562-563 

 in avian serum, 545, 562 

 tests for, 564-565 

 Chitin, relation to pneumococcal poly- 

 saccharides, 259 

 Cholecystitis, Pneumococcus in, 226 

 Cholesterol, effect on hemolysin, 83, 



84 

 Cinchona derivatives. See Chemo- 

 therapy 

 Clasmatocytes in natural immunity, 



432 

 Classification of Pneumococcus. See 

 Electrophoretic potential; Sero- 

 logical classification 

 Coal-tar dyes. See Chemotherapy 

 Coccus lanc4oU de la pneumonie, 1, 9 

 Colony formation of Pneumococcus, 

 46, 47, 48 

 in dissociation, 147-ldO, 152-154 

 nail form, 6, 7, 8, 11 

 Combining equivalents, precipitation 



tests, 645-647 

 Complement fixation 

 antibodies, 380-382 

 as potency test, 581 



