INDEX 



779 



Complement fixation (cont.): 

 in serological classification, 110 

 technique, 647 

 Con j ugated carbohydrate-proteins, 



immunological behavior, 263-265, 



284-285, 448, 450, 453 

 Conjunctivitis, Pneumococcus in, 226, 



227 

 Convalescent serum in treatment of 



pneumonia, 446 

 Cooper's serological classification, 113- 



115 

 Cow(s), immune serum from, 27, 522 

 Cross-agglutination in serological 



classification, 112 

 Cultivation of Pneumococcus. See 



Growth of Pneumococcus; Media 

 Culture filtrates as antigens, 21, 22, 



23, 24, 25, 27, 335-337, 526-527 

 Cultures. See Dissociation; Growth 



of Pneumococcus; Media 

 Cultures, dead, as antigens. See Anti- 

 gens 

 Cystitis, Pneumococcus in, 226 



Dacryocystitis, Pneumococcus in, 227 

 Danysz effect in interaction of poly- 

 saccharide and immune serum, 

 269 

 Dawson's classification, 161-167 

 Death-point, thermal, of Pneumo- 

 coccus, 51 

 Denaturation of antibody, 560 

 Dermal allergy. See Allergy; Skin re- 

 actions 

 Dermal pneumonia in rabbits 

 chemotherapy of, 516 

 in potency tests on serum, 182 

 in tests on action of polysaccha- 

 ride-splitting enzymes, 182, 310- 

 311 

 in tests on resistance, 182 

 production of, 181, 182 

 Dextran, 70, 261 

 Diagnostic serum 



immune serum, horse and rabbit, 



593-595 

 preparation, 592-596, 663-664 



Differential media. See Media, differ- 

 ential 

 Diplococcus lanceolatus, 1, 19 

 Diplococcus pneumoniae, 1, 13, 18 

 Diplococcus pneumoniae Weichsel- 



baum, 1 

 Diplokokkus lanceolatus pneumoniae, 1 

 Dispensing and labeling antipneumo- 



coccic serum, 590-591, 596 

 Dissociation of Pneumococcus 

 bacteriophage, 150 

 colony formation, 147-150, 152-154 

 comparison of systems, 163 

 composite cultures, 140-141 

 daughter colonies, 149 

 early observations, 24, 26, 27, 135-137 

 effect of animal organs, 156 

 effect of charcoal, optochin, yeast, 



144-145 

 effect of immune serum, 137, 139, 



145-147 

 Fldtterformen, 152 

 forms a, b, c, d, and e, 152 

 in S. haemolyticus, 166 

 in vivo variation, 143, 145-147 

 later observations, 137-156 

 modifications A, B, and C, 139-140 

 modified pneumococci, 136 

 P-C variants, 153 

 phantom colony, 153 

 piantication, 136 

 polyphasic cycle, 154 

 unsolved problems, 614-615 

 virulence, 140-141, 212 

 See also Rough (Ft) forms; Smooth 

 (S) forms; Transformation; Va- 

 riants 

 Dog(s), susceptibility to Pneumo- 

 coccus 

 inoculation, 194, 195 

 meningitis, 195 

 pathological processes, 195 

 septicemia, 195 

 Drug-fastness of Pneumococcus, 519- 



520 

 Drugs 



action in relation to pneumococcal 

 types, 514-515 



