INDEX 



A substance, blood-group specific, in 

 relation to capsular polysaccha- 

 ride, 287-288 

 A substance of Pneumococcus 

 as antiopsonin, 400 

 comparison with acetyl polysaccha- 

 rides, 285 

 effect of alkali, 277 

 in anaphylaxis, 450 

 in lung filtrate, 268 

 interaction with immune serum, 269 

 isolation, 265 

 properties, 266-268 

 Abscesses, Pneumococcus in, 19, 20 

 Accessory substances. See Growth of 



Pneumococcus 

 Acetic acid in carbohydrate fermen- 

 tation, 71 

 Acetyl carbohydrate-azoproteins, anti- 

 genicity, 285 

 Acetyl group 

 instability, 279 



relation to immunological activity 

 of Pneumococcus, 278-288 

 Acetyl polysaccharide(s), 277-288 

 A substance of Pneumococcus com- 

 pared with, 285 

 analyses, 281 

 antigenicity, 283 

 excretion in urine, 284 

 in precipitation, 371 

 protective antibodies induced by, 411 

 uronic acid in, 280 

 Acid(s)./Sc« Acid formation by Pneu- 

 mococcus ; Agglutination ; Bile sol- 

 ubility; Carbohydrate fermenta- 

 tion by Pneumococcus; Chemo- 

 therapy 

 Acid formation by Pneumococcus 

 acetic acid, 71 

 effect of serum on, 71 

 formic acid, 71 

 from dextrose, 70 

 from galactose, 70 



Acid formation by Pneumococcus 

 (cont.) : 



from glucose, 71 



from inulin, 70 



from lactose, 70 



from maltose, 70 



from raffinose, 70 



from saccharose, 70 



lactic acid, 70-71 

 Active immunity to Pneumococcus. See 



Immunization, active 

 Agglutination 



acid, 109, 110 



as potency test, 582 



culture, 123 



early observations, 24, 25, 27 



in serological classification, 26, 103- 

 118, 359-360, 361-362 



of variants, 140, 362-363 



quantitative determination, 367 



slide, in type determination, 127-131 



technique, 641 



See also Agglutinins 

 Agglutinin-absorption in serological 



classification, 110, 111, 362 

 Agglutinins, 355-364 



chemical nature, 364 



early observations, 356 



effect of alien infection, 363 



identity with precipitin, 367 



in blood of animals, 363-364 



in blood of pneumonia patients, 

 357-361 



in empyema fluids, 441 



in lobar pneumonia, 438 



in swine serum, 431, 432 



natural, 423, 436 



opsonins, relation to, 431 



preservation, 357 



See also Agglutination 

 Alcohol, effect on resistance, 190 

 Aldobionic acid 



capsular polysaccharide, as constitu- 

 ent, 245, 246 



