772 



INDEX 



Aldobionic acid (cont.): 



in cultivation of SIII bacillus, 308 

 in precipitation, 375 

 Alkaligenes viscosus, immunological 



relation to Type I, 262 

 Allergy 



actively induced, 447-449 

 dermal, 455-474 

 in experimental infection, 448 

 ophthalmic reactions. See Ophthal- 

 mic reactions 

 passive sensitization, 449-454 

 relation to immunity, 454-455 

 See also Skin reactions 

 Alveolar exudate, Pneumococcus in, 6 

 American Drug Manufacturers' As- 

 sociation, potency test, 570, 651- 

 653 

 Amino group in precipitation, 377 

 Amoss' method of type determination, 



129-130 

 Amylase in Pneumococcus, 67 

 Anaerobic strains of Pneumococcus, 



44, 116 

 Anaphylaxis 



A carbohydrate, 450 



capsular polysaccharide, 255, 448, 



449, 454 

 cellular carbohydrate, 270, 451, 454 

 conjugated carbohydrate-proteins, 



264 

 gluco-globulins, 450, 452, 453 

 nucleoprotein, 451 

 passive sensitization, 452-453 

 Type VIII polysaccharide, 275 

 Animal host. See Host response; 



Pathogenicity of Pneumococcus 

 Animal inoculation and transforma- 

 tion of type, 158-160 

 Animals, experimental. See Patho- 

 genicity of Pneumococcus; Skin 

 reactions; and under particular 

 animal 

 Antiblastic immunity, 420-421 

 Antibodies to Pneumococcus, 355-426, 

 436-442, 619 



Antibodies to Pneumococcus {cont.)i 



agglutinins, 355-364 



antihemotoxin, 382-383 



antiopsonins, 398-401 



antiphagins, 398 



antitoxins, 383-386 



bactericidins, 382 



complement-fixing, 380-382 



heterophile, 387-388 



in blood during pneumonia, 437-442 



molecular weight, 415-418 



nature, 23, 364, 411-418 



phagocytosis, 388-406 



precipitins, 365-379 



protective. See Protective anti- 

 bodies to Pneumococcus 



unsolved problems, 619-620 

 Antigen-antibody balance in lobar 



pneumonia, 360 

 Antigen-antibody solution, 408, 413, 



418, 547 

 Antigenicity 



and virulence, 25, 524-526 



of Pneumococcus, 323-354 



of polysaccharides. See Polysaccha- 

 rides 



of protein fractions. See Protein 

 fraction (s) 



of purpura-producing principle, 89 



of rough and smooth forms of 

 pneumococci, 150, 342, 344 



of toxins, 93, 97, 338-340 



See also Antigens 

 Antigens 



administered by buccal membrane, 

 347 



administered by inhalation, 341, 

 346, 348 



administered by injection, 341, 342, 

 343-346, 347 



administered by intrabronchial in- 

 sufflation, 343-348 



administered by intraocular instil- 

 lation, 347 



administered by oral route, 348-351 



antivirus, 336-337, 346 



bacterial extracts, 335 



