784 



INDEX 



Isolation (cont.) : 



of Pneumococcus (cont.): 

 by blood cultures, 628, 636 

 by direct cultures, 36 

 by mouse methods, 35, 626-630 

 by plating method, 627-628 



of protective antibodies. See Pro- 

 tective antibodies 



of protein fractions, 242, 636 



of somatic carbohydrate, 636-637 



Kapselbacterium, 13 

 Koch's law, fulfilment, 2, 9, 16 

 Krumwiede method of type determi- 

 nation, 124-125, 630, 631 



Labeling antipneumococcic serum, 



590-591, 596 

 Lactase in Pneumococcus, 68 

 Lactic acid in carbohydrate fermen- 

 tation, 70-71 

 Lactose, fermentation by Pneumococ- 

 cus, 68 

 Laurie acid in chemotherapy, 509 

 League of Nations, Health Organisa- 

 tion, potency tests, 569, 650-651 

 Leucocidin, 91-93, 202 

 Leucocytes. See Phagocytosis 

 Leuconostoc mesenteroides, dextran 



from, 70, 261-262 

 Levan 



from B. mesentericus and B. sub- 

 tilis, 70 

 Lipases in Pneumococcus. See Lipoly- 



sis 

 Lipids 



as antigens, 253 

 in agglutination, 384 

 in complement fixation, 381 

 in horse serum, 384, 563 

 in immune rabbit serum, 384 

 in precipitation, 384 

 Lipolysis by Pneumococcus, 66-67 

 esterase, 66 

 of benzylacetate, 67 

 of glyceryl tri-acetate, 66 

 of methyl n-butyrate, 67 

 of phenylacetate, 66 



Lipovaccine, 483, 492, 495, 497, 498 

 Lister's serological groups, 107-108 

 Lobar pneumonia 



agglutinins, 438 



antigen-antibody balance, 360 



associated with endocarditis, menin- 

 gitis, pericarditis, pleuritis, 8 



associated with various other infec- 

 tions, 226 



C Fraction, 441 



in cats, 193 



in monkeys, 192, 193 



mixed infections, 121, 217 



opsonins, 438 



percentage distribution of serologi- 

 cal types, 217-219 



pneumococcal types, 216-219 



Pneumococcus in, 216-219 



precipitins, 441 



protective antibodies, 438, 440 



serum treatment, 598-612 



skin reactions in, 460-466 



Streptococcus in, 217 



vaccine therapy, 503-506 



See also Pneumonia 

 Lung puncture, 6 

 Lungs, Pneumococcus in, 5, 14, 17, 18, 



229-230 

 Lung-toxic principles in autolysates, 98 

 Lysis of Pneumococcus 



by bile. See Bile solubility 



by saponin, 58, 59, 60 



by sodium hydroxide, 59 



by sodium linoleate, 59, 60 



by sodium oleate, 59 



by tribasic sodium phosphate, 59 



of variants, 153 



relation to proteolysis, 54 



Macacus cynomolgos, 193, 368 

 Macacus rhesus, 192, 193 

 Macacus syrichtus, 192, 193 

 Macrophages in natural immunity, 



405, 432 

 Maltase in Pneumococcus, 68 

 Man 



epidemics of pneumonia in, 10, 224- 

 225 



