INDEX 



791 



Potency tests on antipneumococcic se- 

 rum (cont.) : 

 Health Organisation of the League 



of Nations, 569, 650-651 

 immune nitrogen, amount in SSS- 

 antibody precipitates, 584 



in vitro tests, 580-584 



in vivo tests, 565-580 



Massachusetts Antitoxin and Vac- 

 cine Laboratory, 573-574, 653-661 



mouse protection test, 407-408, 567- 

 576, 653-661 



National Institute of Health, 567, 

 592, 648-650 



precipitation, 373, 374, 375, 582, 642- 

 647 



protocols and records, 659-661 



Quellung reaction (Neufeld), 581 



Schwellenwert, 408, 575 



tests of therapeutic effects, 576-579 



United States Hygienic Laboratory, 

 567, 648-650 



unsolved problems, 621 



water test, 580-581 



zonal effects, 575 

 Precipitation 



as potency test, 373, 374, 375, 582, 

 642-647 



immunological relation to Gono- 

 coccus, 248, 370 



inhibition zone, 372, 583 



mechanism, 370-377 



of soluble specific substance in urine, 

 123-124, 240, 633-635 



quantitative relations in, 373, 378 



specific flocculation, 253, 368 



See also Precipitation tests; Pre- 

 cipitin (s) 

 Precipitation tests 



combining equivalents, 645-647 



modified routine, 644-645 



nitrogen determination, 643-644 



on urine, 123-124, 633-635 



optimal proportions, 642-643 

 Precipitin (s), 365-379 



aldobionic acid in precipitin reac- 

 tion, 375 



Precipitin (s) (cont.): 



and precipitinogen, balance be- 

 tween, 372 

 antiprotein, 367-368 

 C Fraction, 368-370, 441 

 correlation with other antibodies, 



377-379, 584-585 

 identity with agglutinin, 367 

 in blood, 125, 365-379 

 in empyema fluids, 441 

 index, 372 



microestimation, 375 

 natural, 428 

 normal, 433 

 type-specificity, 366 

 Precipitinogen 



and precipitin, balance between, 372 

 in urine, 123-124, 366, 633-635 

 Preservatives for antipneumococcic 



serum, 557-559, 588-589, 596 

 Prophylaxis, vaccines in, 494-503 

 Protease in Pneumococcus, 66 

 Protection tests 

 in potency determination of anti- 

 pneumococcic serum, 407-408, 

 567-576, 653-661 

 in serological classification, 104, 



105, 106, 108, 111, 113, 114 

 in type determination, 120-122, 



626-630 

 limitations, 571-576 

 mice, host response of, 420, 572, 574 

 rabbit in, 121, 408 

 Schwellenwert, 408, 575 

 Protective antibodies to Pneumococ- 

 cus, 407-420 

 chemical nature, 411-418 

 concentration, 547-556 

 early observations, 407 

 globulin, 26, 416-418 

 in avian serum, 410 

 in immune rabbit and horse serum. 



See Immune serum 

 in lobar pneumonia, 438, 440 

 induced by acetyl polysaccharides, 



411 

 induced by capsular polysaccha- 

 rides, 411 



