INDEX 



799 



Viability of Pneumococcus, 49-52 

 Virulence of Pneumococcus, 196-212 

 and antigenicity, 25, 326-327, 524- 



526 

 and antivirus, 337 

 and avenue of inoculation, 200 

 and bile solubility, 56 

 and dissociation, 140-141, 212 

 and purpura, 88 

 and respiratory changes, 82, 151 

 changes in variants, 82, 140-141, 151, 



212 

 degradation, 211-212 

 determination, 200-202 



electrophoretic potential, 201 



mice, 200 

 effect of cultural conditions, 203-205 



carbon dioxide, 204 



cinchona derivatives, 519-520 



concentration of meat in medium, 

 204 



eggs, 205 



frequency of transfer, 204, 205 



glucose, 204 



hydrogen ion concentration, 204 



milk, 203 



nitrogen, 204 



oxygen, 204 



peptone, 38 



serum, immune and normal, 204 



temperature, 204 

 exaltation, 27, 204 



artificial, 210-211 

 freshly isolated strains, 197-199 

 in relation to toxins, 93, 98 

 influence on immunological re- 

 sponse, 326-327 

 maintenance, 20, 648-649, 651, 653 

 media for growth of virulent cul- 

 tures, 634 

 number of cocci required to infect, 



199-200 



Virulence of Pneumococcus (cont.): 

 relation to respiration, 82, 151 

 strain variations in, 205-206 

 substances enhancing, 202-203 

 autolysates, 202-203 

 capsular polysaccharides, 203 

 leucocidin, 202 

 mucin, 202 



soluble specific substance, 203 

 test for, 653-654 

 toxins, 93, 98 

 virulin, 91, 98, 202 

 unsolved problems, 616-617 

 variants, 82, 140-141, 212 

 weight factor of animals, 200 

 with respect to animal species, 206- 

 210 

 animal passage, 207, 210, 211 

 guinea pigs, 206, 207 

 mice, 206, 207 

 rabbits, 206, 207-210 

 Virulin, 91, 98, 202 

 Virus pneumonico, 1, 20 

 Viscosity of capsular polysaccharides, 



297 

 Vuzine 

 as germicide, 515 

 in chemotherapy, 512 



Welch bacillus, hemotoxin in, 86 



Xanthoprotein, formation by Pneumo- 

 coccus, 75 



Yeast 



as accessory substance in cultiva- 

 tion of Pneumococcus, 45 



effect in dissociation, 144 



relation to polysaccharide of Pneu- 

 mococcus, 422-423 



