MITOSIS 



13 



they are attached does not appear to be a satisfactory explanation of their 

 movements (Fig. 3, F). 





Fig. 3. — Diagram of Nuclear Division by Mitosis. (After Agar, 1920. 



A. Resting nucleus with centrosome. 



B. Early prophase with dividing centrosome. 



C. Middle stage of projjhase: appearance of spindle and dividing chromosomes. 



D. Late prophase. 



E. Metaphase with divided chromosomes as equatorial plate. 



F. Anaphase: separation of daughter chromosomes. 



G. Telojihase: aggregation of chromosomes. 



H. Completion of nuclear and cell division and reconstructed daughter nuclei. 



TELOPHASE. — The spindle fibres gradually disappear, the nuclear 

 membrane re-forms around the chromosomes, which gradually become 

 transformed into the linin network and chromatin characteristic of the 



