ENTAMCEBiE OF OTHER MAMMALS 227 



the fact that cysts and free forms with over twenty nuclei occiirred. 

 The multinucleated free forms are regarded as schizonts, and a figure 

 shows what the author regards as division into daughter amoebae. It 

 is far from clear that these free forms are not cysts, and the figure illus- 

 trating the escape of the daughter amoebae from an enclosing membrane 

 which he says is present might well be interpreted as a ruptured cyst 

 from which the nuclei are being extruded by pressure. Though the 

 author refers to the amoeba as a new species, E. multinudeata, it 

 is evident that he may have been dealing with multinucleated formes of 

 E. ■pitheci, and that this amoeba comes into line with E. coli, in which 

 similar stages are by no means uncommon. In stained and cleared 

 preparations, as pointed out above, it is often exceedingly difficult to 

 decide whether a form is actually encysted or not. The writer has seen 

 free forms and cysts of an amoeba resembling E. jyitlieci in Cercopithecus sp. 

 of West Africa, and with Dr. G. C. Low the cysts alone in the faeces of a 

 gorilla. 



Dobell (1926) has cultivated from monkeys four species of amoeba 

 including E. nuttaUi. With the last, the complete history of which, in- 

 cluding excystation, has been studied in cultures, he has produced in 

 kittens a dysentery which difiers in certain respects from that resulting 

 from inoculation of E. histolytica. 



Brug (1923) has discovered in Macacus cynomolgus a small race of an 

 amoeba corresponding with the small race of E. histolytica in man. On 

 the assumption that these human amoebae represent a distinct species {E. 

 tenuis), he gives the name E. cynonwlgi to the form in the monkey. It is 

 possible, however, that it is merely a small race of E. nuttaUi. 



ENTAMCEB^ OF OTHER ANIMALS. 



Entamoebae are of common occurrence in the intestine of animals, 

 while occasionally they occur in the mouth of the dog and horse, as noted 

 above (p. 224). Spontaneous amoebic dysentery in dogs has been described 

 by Kartulis (1891, 1913) in Egypt, Darling (1915) in Panama, and Ware 

 (1916) in India, Fischer (1918) in China, and Bauche and Motais (1920) 

 in Cochin-China. In one case noted by Kartulis the dysentery was 

 associated with abscess of the liver. As the dog is known to be infectible 

 with E. histolytica, it seems probable that it was actually this species 

 which was producing the disease. Darling (1915), without differentiating 

 it from E. histolytica, proposed the name E. roiaticiini for the amoeba 

 producing canine amoebic dysentery. Franchini, F. (1920 1923), recorded 

 a case of spontaneous amoeboid dysentery in a cat in Italy. It was con- 

 cluded that the amoeba was E. histolytica. 



