338 



FAMILY: TRYPANOSOMID^ 



and nucleus, and new flagellum formation, the division of the body is 

 delayed for some reason (Fig. 160, 17-20). The daughter kinetoplasts 

 and nuclei may proceed to a further division, giving rise to forms with 

 four sets of these structures. Such forms are sometimes seen in actively 

 multiplying trypanosomes like T. brucei in the blood of a rat, where in- 

 dividuals with four nuclei, four kinetoplasts, and four undulating mem- 

 branes and flagella arise. By a further division of one or more of the 

 nuclei and kinetoplasts, still more complicated forms are produced. 



Fig. 161. — Crithidia enryoplithalmi from Fig. 162. — Crithidia euryophthalmi 



Intestine of the Bug, EuryopJithalmus 

 convinus (x ca. 2,400). (After McCul- 

 LOCH, 1919.) 



Multiple division forms (spheres) in the epithelial 

 cells of the crop. 



FROM Intestine of the Bug, 

 Euryophthalmus convinus ( x 3,500). 

 (After McCuleocii, 1919.) 



Forms showing what is described as in- 

 ternal budding. 



During the development of T. lewisi in the flea, the intracellular phase 

 results in the formation of multinucleate forms, in which as many as 

 sixteen trypanosomes are represented before cytoplasmic division occurs 

 (Fig, 200, 5-11). A similar form has been described by McCulloch (1917) 

 as an intracellular phase of the development of Crithidia euryophthalmi 

 in the crop of the bug, Euryophthalmus convivus (Fig. 161). Multiple 

 segmentation forms of T. lewisi also occur in the blood of the rat 

 in the early phases of an infection (Fig. 197). The process has been 



