XU CONTENTS 



CHAPTER 2 



Maleate 285 



Chemical Properties 286 



Inhibition of Enzymes 294 



Effects on Respiration and Glycolysis 302 



Effects on Various Metabolic Pathways 306 



Metabolism of Maleate 311 



Effects on Tissue Function 315 



Effects on Whole Animals 316 



Effects on Mitosis and Growth 322 



Maleamate, Maleimide, and Maleurate 324 



Maleic Hydrazide 326 



CHAPTER 3 



/V-Ethylmaleimlde 337 



Chemical Properties 337 



Inhibition of Enzymes 343 



Effects on Metabolism 356 



Effects on Tissue Functions 358 



Effects on Mitosis and Growth 364 



CHAPTER 4 



Alloxan 367 



Chemical Properties 368 



Diabetogenic Action 380 



Fate of Alloxan in Animals 393 



Effects on Enzymes 395 



Effects on Metabolism 401 



Mechanisms Involved in the Early Hyperglycemia and Hypoglycemia . 405 



Mechanism of the Diabetogenic Action 408 



Some Effects on Tissues Other Than the Pancreas 417 



Effects on Cell Growth and Proliferation 418 



CHAPTER 5 



Quinones 421 



Chemical Properties 423 



Reactions of the Quinones 435 



Inhibition of Enzymes 445 



Effects on Electron Transport Systems 470 



Effects on Oxidative Phosphorylation 477 



Effects on Glycolysis 481 



Effects on Respiration 488 



Effects on Various Metabolic Systems 493 



