950 



SUBJECT INDEX 



chloropicrin, 282 



iV-ethylmaleimide, 343-344 



fluoroacetamide, 27 



iodoacetamide, 27, 45-46, 272 

 pH effects, 45-46 



iodoacetate, 25-27, 50, 272 



protection by ethanol and NAD, 27 

 rate of inhibition, 26, 50 



iodoacetate ethyl ester, 278 



maleate, 296 



proprionamide, 27 



SH reagent comparison, 797 

 Aldehydercytochrome c oxidoreductase, 



arsenite, 623 



SH reagent comparison, 797 

 Aldehyde dehydrogenase, see also Al- 



dehyde-cytochrome c oxidoreductase, 



arsenicals, 623-624, 645, 648 



arsenite-mercaptoethanol, 660 



iV-ethylmaleimide, 344, 346 



iodoacetate, 46, 53 



protection by acetaldehyde and 

 NADP, 46 



SH reagent comparison, 797 



silver, 797 

 A]dehyde:indophenol oxidoreductase, ar- 

 senite, 623 

 Aldehydemitrate oxidoreductase, p-ben- 



zoquinone, 446 

 Aldehyde oxidase, 



arsenite, 618, 624, 647 



quinones, 446, 466 

 Aldolase, 



carbamylmethylation by iodoaceta- 

 mide, 49 



iodoacetamide, 71 



iodoacetate, 71 



maleic hydrazide, 330 



SH reagent comparison, 797 



silver, 797 

 Algae, see also specific organisms, 



growth of, 

 arsenicals, 769 

 quinones, 573-574 



keto acid accumulation, arsenite, 670 



respiration, phthiocol, 582 

 Alkaline phosphatase, see Phosphatase 



(alkaline) 



AUiinase (alliin lyase), A'^-ethylmaleimide, 



346 

 Alliin lyase, see AUiinase 

 Allohydroxy-D-proline oxidase, iodoace- 

 tate, 149 

 Allomyces macrogynus, 



acetate oxidation, iodoacetate, 96 

 respiration (endogenous), iodoacetate, 

 113, 122 

 respiration (glucose), 



arsenite, 678 



iodoacetate, 96, 122 

 Allose kinase, iodoacetamide, 53 

 Alloxan, 



acetylcholine response, 417 

 antibody formation, 405 

 ascorbate oxidation by, 378 

 ATPase in islet cells, 413 

 bacterial growth, 418 

 bartonellosis, 418 

 blood glucose, 381-383, 392-393 

 blood pressure, 409 

 carcinostasis, 419 

 central nervous system, 417 

 chelation with metal ions, 378 

 chemical properties, 368-380 

 creatine excretion, 383 

 determination of, 379-380 

 diabetogenic action, 367, 380-393, 400- 

 401, 408-417 



antagonizing substances, 388-391 



blood glucose levels, 381-383 



discovery of, 367 



enzyme inhibitions possibly respon- 

 sible, 400-401 



factors in susceptibility, 383-384 



islet cell changes, 380-381 



islet cell GSH, 386-388 



mechanism of, 408-417 



reasons for selective /5-cell damage, 



410-412 



relation to zinc, 414-415 



structure-activity relations, 384-386 

 diabetogenic doses, 383-384 

 diastase excretion, 415 

 embryogenesis, 418 

 enzyme inhibitions, 395-401 



