SUBJECT INDEX 



955 



toxicity, 595, 597, 705-707, 709-710, 



712-733, 740-747 

 arsenite, 713 

 capillary theory, 726-729 

 mechanisms involved, 731-733 

 metabolic relations, 729-731 

 organic arsenoxides, 714-715 

 organic arsonates, 715-716 



tricarboxylate cycle, 662-667 



trypanocidal doses, 747-749 



trypanosomes, 734-749, 752-754 

 binding in cells, 734, 736-737 

 dosage range, 747-749 

 kinetics of action, 737-738 

 mechanisms involved, 752-754 

 potencies, 735 

 reversibility, 753-754 

 structure-activity relations, 739-747 



urinary excretion of, 782-783 



urine volume, 705-706 



uterus, 709 



vesication, 727-729 



viruses, 756 

 Arsenic eaters, 725 

 Arsenic trioxide, solubility of, 602 

 Arsenious acid, see Arsenite 

 Arsenite, see also Arsenicals, 



acetate oxidation, 665 



acetoacetate utilization, 690 



auxin antagonism by, 771 



bioluminescence. 697 



blood glucose, 729-731 



blood lactate, 598, 672 



body fat, 689 



body temperature, 597 



carcinogenicity, 773-775 



C-l/C-6 ratio, 676-677 



cellulose biosynthesis, 673 



central nervous system, 597 



cholesterol biosynthesis, 691 



cholesterol levels in tissues, 692 



citrate metabolism, 667 



coenzyme A level in yeast, 689 



coliphage proliferation, 756 



compared with arsenate, 596 



complexes with cations, 603 



coproporphyrin excretion, 696 



edema production, 727 



Entamoeba growth, 735 



epinephrine response, 710-711 



ethanol metabolism in rabbits, 697 



fatty acid biosynthesis, 660, 690 



fermentation by yeast, 597, 775 



gastric acid secretions, 703, 705 



glucose oxidation, 676 



glutamate oxidation, 695 



growth of animals, 725-726 



growth of tissue cultures, 769 



hematopoietic depression, 713 



histamine release, 709 



hypothermia, 713 



ionization of, 602 



lactate oxidation, 665 



lanosterol accumulation, 691 



lethal doses, 717-718 



leukemia, 772 



muscle, 597, 708 



Na+-K+ levels in skin, 194 



nitrite oxidation, 617 



nitrogen balance, 597-598, 692-693 



nuclear effects, 770-771 



nucleic acid biosynthesis, 697 



oxidation by bacteria, 786 



oxidation in tissues, 598, 785-786 



oxidation-reduction potential, 603 



paramecial motility, 750 



Pasteur reaction, 676 



pentose-P pathway, 677 



phosphate uptake by yeast, 658 



photophosphorylation, 696 



photosynthesis, 696-697 



polymerization of, 602-603 



proline oxidation, 695 



protein metabolism, 692-693 



protozoal motility, 750 



purine biosynthesis, 697 



purity of, 603 



pyruvate accumulation, discovery of, 



598 



pyruvate dismutation, 662-663 



pyruvate oxidation, 664-666 



reaction rates with thiols, 610-611 



resistance factors in paramecia, 759 



resistance in mammals, 764-765 



resistance in tissue cultures, 764 



