988 



SUBJECT INDEX 



Kerateine, reaction with arsenicals, 614- 



615 

 Keratine, 



reaction with iodoacetate, 17 

 reaction with quinones, 443-445 

 Keto acids, see also Pyruvate and a- 

 Ketoglutarate, 



accumulation of, arsenicals, 668-674 

 urinary excretion of, 

 arsenite, 673-674 

 iodoacetate, 321 

 maleate, 320-321 

 malonate, 321 

 mercurials, 321 

 phlorizin, 321 

 ^-Ketoadipate chlorinase, arsenite, 617 

 2 - Keto - 3 - deoxy - d - araho - heptonate - 7 - 

 phosphate synthetase, iodoacetate, 126 

 a-Ketoglutarate, see also Keto acids, 

 accumulation of, arsenicals, 668-674 

 blood levels of, 

 iodoacetate, 250 

 maleate, 317 

 oxidation of, 



arsenicals, 621, 645, 666-667 

 iV-ethylmaleimide, 356 

 iodoacetate, 95 

 maleate, 307-308 

 a-Ketoglutarate dehydrogenase, 

 iodoacetamide, 91 

 iodoacetate, 91 

 SH reagent comparison, 807 

 a-Ketoglutarate: indophenol oxidoreduc- 



tase, arsenite, 631 

 a-Ketoglutarate:NAD oxidoreductase, ar- 

 senite, 631 

 a-Ketoglutarate oxidase, 



arsenicals, 618, 631, 646, 649, 651, 653 

 iV-ethylmaleimide, 349 

 iodoacetamide, 272 

 iodoacetate, 272 

 maleate, 297, 300 

 a-Ketoglutarate reductase, iodoacetate, 



56 

 2-Keto-4-hydroxyglutarate aldolase, N- 



ethylmaleimide, 350 

 a-Ketoisocaproate decarboxylase, arse- 

 nite, 656 



4-Ketoproline reductase, arsenite, 656 

 Kidney, see also Nephrotoxicity, 

 acetate oxidation, arsenite, 665 

 acetoacetate utilization, arsenite, 690 

 alloxan levels in, 394 

 arsenite binding in cells, 784 

 arsenite binding in vivo, 723-724 

 arsenite-resistant tubular cells, 765 

 bicarbonate resorption, maleate, 318 

 bromoacetate levels in vivo, 246 

 cholesterol levels in, arsenite, 692 

 citrate accumulation in, iodoacetate, 97 

 citrate oxidation, arsenite, 667 

 Cl^ resorption, iodoacetate, 191 

 glucose transport, 



iodoacetate, 191-192 



maleate, 318 

 glucose utilization, iodoacetate, 137 

 glycolysis (anaerobic) 



alloxan, 403 



iodoacetate, 66 

 GSH levels in vivo, alloxan, 387 

 iodoacetate levels in vivo, 245 

 keto acid accumulation, arsenite, 598, 

 671 



lactate accumulation in, arsenite, 672 

 lactate levels in vivo, iodoacetate, 108 

 maleate metabolism in, 312 

 Na+-K+ transport, 



arsenite, 702-703 



p-benzoquinone, 503 



iodoacetate, 175, 185-186, 192, 251 



maleate, 318 

 oxidative phosphorylation, iodoacetate, 

 60-61 

 PAH transport, 



arsenite, 704 



iodoacetate, 179, 192-193 



maleate, 318 

 phenol red transport, 



arsenite, 704 



iodoacetate, 179, 187, 191 

 pyruvate oxidation, arsenite, 665 

 respiration, 



alloxan, 402 



arsine, 792-793 



benzoquinones, 488, 503 



maleate, 305 



