1006 



SUBJECT INDEX 



Phenol, 



lethal doses, 518 

 mitosis, 524, 528 



Phenoldialurate, diabetogenic action, 385 



Phenol oxidase, see Catechol oxidase 



Phenol-phosphate, fibroblast mitosis, 528 



Phenol red, renal transport of, 

 arsenite, 704 

 iodoacetate, 179, 187, 191 



Phenylalanine deaminase, iodoacetamide, 

 151 



Phenylalanine 4-hydroxylase, arsenite, 

 656 



Phenylalloxan, diabetogenic action, 384 



Phenylarsenoxide, 

 binding in blood, 783 

 binding in tissues in vivo, 724 

 binding in trypanosomes, 734, 736 

 citrate oxidation, 667 

 Colpidium killing, 751 

 cyclic thioarsinites from, 612 

 enzyme inhibitions, 618, 622-623, 625- 

 627, 631, 633, 637, 639, 642-645, 650, 

 654-655, 723 



growth of tissues cultures, 769 

 a-ketoglutarate oxidation, 667 

 lactate oxidation, 665 

 lethal doses, 719 

 malate oxidation, 667 

 paramecia, 750-751 

 permeability to, 700 

 pyruvate accumulation in brain, 671 

 pyruvate oxidation, 665, 667 

 reaction rates with thiols, 610-611 

 sarcoma growth in vivo, 772-773 

 skin irritation, 727-728 

 succinate oxidation, 667 

 Tetrahymena, 750 

 tissues distributions of, 780-781 

 trypanocidal action, 735 

 urinary excretion pattern of, 779, 787 

 yeast respiration, pH effects, 775 



Phenylarsenoxides, 



comparison of toxicity and antiproto- 

 zoal activities, 739-747 

 ionization constants, 777 

 oxidation-reduction reactions, 604 

 rates of oxidation, 604-605 



trypanocidal actions, pH effects, 775- 



778 



trypanocidal doses, 747-748 



urinary excretion of, 783 

 Phenylarsenoxide-thioglycolate, urease, 



790 

 Phenylarsonate, 



fibroblast growth, 770 



lethal dose, 719 



tissue distributions, 780-781 



urinary excretion of, 787 

 Phenylarsonates, 



complexes with metal ions, 606 



rates of reduction, 604-605 



reactions with thiols, 608-609 



trypanocidal doses, 748 

 Phenylarsonic acids, ionization constants, 



604-605 

 Phenylarsonous acids, see Phenylarse- 

 noxides 

 Phenyl-p-benzohydroquinone, virus pro- 

 liferation, 580 

 Phenyl-j?-benzoquinone, central nervous 



system, 513 

 Phenyldichlorarsine, see Dichlorophenar- 



sine 

 m-Phenylenediamine, 



pyruvate decarboxylase, 590 



respiration, 592 

 p-Phenylenediamine, 



carcinostasis, 593 



edema production, 594 



pyruvate decarboxylase, 590 



reaction with alloxan, 377-378 



respiration, 592 



succinate oxidase, 589 



toxicity, 593 

 p-Phenylenediamine, see also p-Benzo- 



quinonediimine, 



blood vessels, 594 



carcinostasis, 593 



chemical properties, 586-587 



c-mitosis in onion roots, 537 



conjunctival inflammation, 593 



edema production, 594 



enzyme inhibitions, 588-592 



formation from carcinogens, 586 



free radicals from, 587 



