130 



BACTERIOLOGICAL CHEMISTRY 



met alio -organic compounds of arsenic, antimony and 

 bismuth, to derivatives of quinine, to the triphenyl 

 methane series of dyes, to acid bis-azo dyes, such as 

 trypan-red and trypan -blue, to acriflavine and to the 

 amidines. 



Leishmania are susceptible to pentavalent antimony 

 compounds such as stibenyl, ^^-aminophenyl sodium 



ONa 



stibonate, 



NH2< 



>Sb = , 



\ 

 OH 



or stibacetin, CH3C0.NH< 



ONa 



/ 

 >Sb = 



\ 

 OH 



and to the amidines. 



Amoebae are susceptible to chinoform, iodohydroxy- 



SOsNa 



quinoline sulphonate. 



and to the pentavalent 



arsenicals acetarsol, 



OH N 



H0< 



OH 



/ 

 )As = 



\^ ' and carbasone, 

 OH 



NH.CO.CH, 



•\ / 



OH 



/ 

 As = 



OH 



Plasmodia are susceptible to quinine, plasmoquin, 

 atebrine, and paludrine. 



Spirochsetes are susceptible to the metallo -organic 

 compounds of arsenic, antimony and bismuth, but are 

 relatively little affected by purely organic drugs. 



