MUCORALES 117 



Mycosis of lung of coiintiy woman, final recovery after several months 

 of treatment with arsenic. See Arch, de Parasitol. 4: 386-389, 1901, for case 

 history and results of inoculations. Nonpathogenic in subcutaneous inocu- 

 lations. 



Mycelium gray (lead color) to mouse gray then grayish brown to yellow. 

 Stolons and rhizoids irregular. Sporangiophores branched in simple clusters, 

 or in corymbs 12-14/x in diameter, 1-2 cm. long ; sporangia 35-80/x,, with mem- 

 brane covered with fine crystalline needles; columella ovoid, pyriform, cutin- 

 ized slightly brownish, 30-70//, long by 24-56/a in diameter; lateral sporangia 

 similar but much smaller ; pedicels rarely ramifying a second time ; spores 

 irregular or reniform, smooth, 4 x 2.5/x. Zygospores unknown. 



Growth on most media very good, but less on peptone broth and on very 

 acid or alkaline media, poor on coagulated sera, amniotic liquid, white of 

 egg, cider, apples, or pears, the latter, however, is good if glycerin or glucose 

 is added. Growth more rapid on solid than on liquid media. [Very full 

 description given in Arch, de Parasitol. 4: 384-408, 1901.] 



Optimum about 37° C. ; growth starts at 22°, at 51-52° very abnormal 

 vegetative growth but no spores. It needs much oxygen. 



Rhizopus rhizopodiformis (Cohn) Zopf, Die Pilze 317, 1890. 



Mucor rhizopodiformis Cohn in Lichtheim, Zeitschr. Klin. Med. 7: 148, 1884. 



Rhizopus Cohnii Berlese & de Toni in Saccardo, Syll. Fung. 7: 213, 1888. 



Pathogenic for the rabbit Avhen injected into peritoneum and veins. 

 Ziegenhom (1886) was unable to modify pathogenicity of spores. T. Smith 

 (1920) reports this organism on membranes and in lungs and digestive tracts 

 of fetus but probably it was R. equinns. 



Mycelium white, then mouse-gray, rising as a spider web above the sub- 

 strate. Stolons forming rhizoids at point of contact with substrate, in brown- 

 ish bouquets. Sporangiophores isolated or grouped, erect or incurved, short, 

 120-125/i, not branched, with brownish membrane enlarging in an apophysis. 

 Sporangia spherical, 60-110/t usually about 66/a, blackish at maturity, smooth 

 with incrusted membranes. Columella forming with the apophysis an ovoid 

 or pyriform organ, 50-75/i broad, membrane smooth and brownish. Spores 

 usually spherical, small, 5-6/x, without angles, smooth, hyaline. Zygospores 

 and chlamydospores unknown. 



Cultural characters are similar to those of Absidia corynibifera (p. 112). 

 Optimum temperature 37-38° C, sporangia after 48 hours, mycelium changing 

 from white to gray. At 12-15° spores germinate on third day, sporangia on 

 fourth or fifth day. At 45° the mycelium is arrested and spores are killed 

 at 68°. 



Doubtful Position 



Rhizomucor septatus (Bezold in Siebenmann) Lucet & Costantin, Arch, 

 de Para.sitol. 4: 362, 1901; Barthelat, Mucorinees pathogenes et les mucormy- 

 coses 52, 1903. 



Mucor septatus Bezold in Siebenmann, Die Schimmelmycosen 97. Wies- 

 baden, 1889. 



