192 



MEDICAL MYCOLOGY 



one per cell, but more may form in elongate cells. The vacuole soon enlarges 

 to occupy about one-half the cell volume. Small, highly refractile bodies ex- 

 hibiting active Brownian movement appear within the vacuoles. These are 

 probably metachromatic corpuscles. Sprouting is still active and the sprout 

 cells may or may not show vacuoles before separation from the parent cells. 

 These adolescent (mote cells of Shrewsbury) cells correspond to the phase of 

 maximum growth ; thereafter the cells begin to store up glycogen preparatory 

 to production of sexual processes or of hypnospores. 



A B^ 



■J©©©© 





13O00f 



iilfii^wiiBM 



10 



11 



Fig. 39. — Types of blastospores. 1, Structure: A, thick-walled; B, stained for glycogen; 

 C, uniguttulate blastospores ; D, biguttulate blastospores ; E, showing refringent granules ; F, 

 degenerating senescent blastospore. S, Spherical blastospores ; S, ellipsoid, short ; h long 

 ellipsoid ; 5, ovoid types ; 6, asymmetric ; 7, stalagmoid or lacrimiform types ; 8, elongate cylindric 

 types; 9, bacilliform types; 10, irregular bacilliform types; 11, still more irregular types from 

 membranous cultures; 12, truncate types; 13, pyriform types; U, arthrospores. (After Lan- 

 geron & Talice 1932.) 



As the culture ages, the adult cell (durable cell of Shrewsbury, Fig. 

 40, 3) appears and may persist unchanged for long periods. It is larger than 

 the preceding types. It contains a large vacuole, usually empty but occasion- 

 ally containing a single fat globule. Fat is stored generally in a single large 

 globule at one of the poles. This globule is usually surrounded by a layer of 



I 



