174 MEDICAL MYCOLOGY 



poor. In Raulin's liquid, growth is fair, white sediment, liquid clear. In Gedo- 

 elst liquid, growth very good. Coagulated serum not liquefied. Gelatin not 

 liquefied in 30 days. 



Zymonema crateriforme (Iludelo, Sartory & Montlaur) Dodge, n. comb. 



Endomyces crateriforme Hudelo, Sartory & Montlaur, C. R. Acad. Sci. 170: 

 1086-1088, 1920. 



Saccharomyces, sp. Hudelo, Sartory & Montlaur, Bull. Sci. Pharmacol. 25: 

 352-357, 1918. 



Isolated from a lesion in the armpit of a young woman. Lesion oval, 3 

 cm. in diameter, erythematous, scaly, reminding one of dry seborrheic eczema. 

 Nonpathogenic to rabbits and guinea pigs, by either subcutaneous, intraperi- 

 toneal, or intravenous injections. On scarification an atypical, evanescent 

 lesion results. 



Submerg'ed mycelium shows yeastlike budding cells, 9-11/a, or oidial cells, 

 15-16/A long. Conidia sprouting from aerial mycelial branches on some sort 

 of sterigmata are variable but usually ellipsoid or ovoid, 5-7 x 6-9//.. Asci 

 appear on solid media and old cultures after 80 hours at 22-23° C. These are 

 usually terminal, rarely intercalary, 4-5/x in diameter, containing 4 spores each. 

 Spores 3-3.5 x 1.75-2/a, with single smooth membrane. 



On Sabouraud agar, colony is small and white, becoming- creamy white, 

 center yellow and irregularly crateriform, finally crackled, appearing- like 

 small sponge. On carrot or potato, colony broader, thicker with several small 

 craters, very much folded, cream white, covered with conidia. On broth 

 gelatin, colony not fully developed before liquefaction on seventh day. After 

 18 days on malt extract, colony appears as thick, dry, folded mat covered with 

 conidia, sediment of yeast cells, feeble fermentation with slightly aromatic 

 odor. Growth similar on beef broth, peptone + glycerol + glucose broth, normal 

 Raulin's solution with g-lucose, lactose, galactose or maltose, or on prune 

 decoction. Sucrose, glucose, fructose fermented, not rafSnose, lactose, galactose, 

 or maltose. Starch paste not liquefied. Milk not coagulated in 34 days. 

 Gelatin liquefied. 



Zymonema albicans (Okabe) Dodge, n. comb. 



Endomyces albicans Okabe, Centralbl. Bakt. I, 111: 181-187, 1 pi., 1929, 

 non aliorum. 



Isolated from 49 cases of thrush, in Japan, and pathogenicity of this strain 

 proved. ["Monilia Candida," a filamentous species with strong- fermentation 

 of sucrose and a strain wdiich completely failed to ferment, also isolated from 

 some of the above cases, but proved to be nonpathogenic] 



Yeast cells spherical or ovoid, 4-6/a in diameter, with giant cells in old 

 cultures reaching 15-20/x, after a time elongating and forming mycelium. 

 Mycelium 3-4/i, in diameter, cells 20-30/x long, rarely up to 80/x. Chlamydo- 

 spores pyriform, spherical or ovoid, 7-12/i, in diameter. Asci in 45 strains 

 1-spored, rarely 2-4-spored, 5-6/a in diameter; ascospores spherical to ellipsoid, 

 3.5-4 X 2.5-3/i., thick-walled, asci found only in the yeast stage, not on the 

 mycelium, produced only on koji extract agar after 4-6 months. 



