ENDOMYCETALES 157 



Neog-eotrichum pulmoneum (0. Magalhaes) O. Magalhaes, Mem. Inst. Os- 

 waldo Cruz. 26: 151-167, Fls. 36-40, 1932. 



Oidium pulmoneum, 0. Mag^alhaes, Brasil Med. 28: 313, 1914. 



Oidium hrasiliense 0. Magalhaes, Mem. Inst. Oswaldo Cruz. 10: 20-61, 11 

 pis., 1918; Ibid. 19: 290, 291, 1926. 



Mycodenna brasiliense Neveu Lemaire, Precis Parasitol. Hum. 69, 1921. 



Monilia hrasiliensis Bn^mpt, Precis Parasitol. ed. 3, 1100, 1922. 



MyceloMastanon hrasiliense Ota, Jap. J. Derm. Urol. 28: [4 Japanese] 

 1928. 



GeotricJmm hrasiliense Ciferri & Redaelli, Ann. Myc. 27: 243-295, 1929. 



Candida hrasiliensis Basgal, Contr. Estudo Blastomycoses pnlmonares 50, 

 1931. 



Case with the usual symptoms of pulmonary tuberculosis. Mycohacterium 

 tuhercidosis not found by any method. NeogeotricJium inoculated into monkeys, 

 reproduced the human disease very closely, and the organism was reisolated. 

 Severe lesions caused in the usual laboratory animals. Full clinical, patho- 

 logic, and therapeutic notes given. 



At first yeast forms prevail, 5-6/a in diameter. These also are the prin- 

 cipal forms found in sputum. Mycelium abundant on carrot and potato, sep- 

 tate, septa disappearing in old cultures. Spores or cysts form bacilliform 

 bodies, rupture, set free spores, and thus reproduce. 



Colonies moist at first, becoming dry and velvety, wrinkled to almost 

 cerebriform, dirty gray or whitish (dirty yellow on carrot). Growth good on 

 Sabouraud agar with maltose and alkaline Sabouraud agar, potato slices, car- 

 rot, Drigalski-Conradi, Endo, Gorodkova, Loeffler media; milk coagulated 6-12 

 days, gelatin liquefied 12-14 days with thick dark brown pellicle, glycerol-gelatin 

 liquefied within 30 days. In simple broth a pellicle, dark gray, thick, no 

 clouding but after scA^eral months a brownish white sediment forms, containing 

 both yeast cells and mycelium. Growth even better in glycerol broth. No 

 fermentation. Acid with sucrose, galactose, nutrose, mannite, fructose, raf- 

 finose, dextrin. 



Protomycetaceae. — This family continues the main line of development 

 from the Coccidioideaceae, with the migration of the ascus nuclei to the wall 

 before spore formation begins. The spore mother cell initials are separated 

 by radial planes of fission and then by periclinal fissures. These then divide 

 into four spores and form a wall, suggestive of conditions found in the proto- 

 spores of the Mucoraceae and in some other groups. There are two well- 

 known genera of obligate parasites of plants, Protomyces and Taphridium. 



In Protomyces pachydermus on dandelion (Taraxacum offici7iale) and P. 

 macrosporus on various membei's of the parsnip family (Umbelliferae) causing 

 various small hypertrophies on stems and leaves of the host, conditions are 

 essentially similar to those in Coccidioides reported by Fonseca (1928), but 

 the need for a resting spore to carry the fungus over unfavorable environ- 

 mental conditions has caused a further development of the aseus. In some 



