]66 MEDICAL MYCOLOGY 



cidioides immitis is already the type of the genus Coccidioides if that species 

 were to be considered the type, it is evident that Blast omycoides would fall into 

 complete synonymy as a stillborn name, a situation wholly inconsonant with 

 Castellani's work, since it is evident from his Manual of Tropical Medicine that 

 he knew that Coccidioides immitis was the type of Coccidioides. A further study 

 of Blast omycoides immitis Cast, shows that it differs in important respects from 

 Coccidioides immitis of the older authors and belongs in Geotrichum. Conse- 

 quently, we prefer to consider B. dermatitidis as his type, but even so, the name 

 falls into synonymy with Zymonema. 



The description of Zymonema has been emended to include the more recent 

 knowledge of the life cycle of this organism, obtained by Moore (1933) in my 

 laboratory. 



Mycelium and sprout mycelium both present, the asci arising from copula- 

 tion branches, often heterogamous, rarely parthenogenetic ; asci typically ovoid 

 or spherical, spores 4-8 per ascus, smooth, ellipsoid to spherical. In the tissues, 

 yeast cells predominate. 



This group is probably much larger than here presented, but the present 

 state of our knowledge regarding the large number of species commonly re- 

 ferred to Monilia by the medical man is such that we have not included them 

 here. (See Chapter XI.) 



It is possible that a further knowledge of the group \\\\\ cause a separation 

 of the species into two or more genera. For the most part they embrace species 

 previously refeiTed to Endoynyces (in the broader sense including the segre- 

 gate Endomycopsis) . They differ from Endomyces by the shape of ascospore, 

 habitat, parasitism, etc. 



Asci 8-spored, following heterogamous copulation, gelatin liquefied after 30 days. 



Colony creamy, moist, then covered with coremia C prickly appearance") and finally 



cottony. Z. dermatitidis. 



Colony creamy, moist, then cottony. Z. capsulatum. 



Asci 2-4-spored, sexuality not reported (perhaps not belonging in Zymonema) . 



Not growing well on ordinary media when first isolated, confined to the Equidae. 



Z. farciminosum. 

 Growing well on ordinary media, reported from primates and inoculable to other 

 mammals. 

 Colony crateriform, yellowish or white. 



Gelatin not liquefied (asci rarely 8-spored). Z. Molardi. 



Gelatin liquefied, colony becoming crackled. Z. crateriforme. 



Colony not crateriform, creamy. 



Not producing pellicle on liquid media. 



Sugars fermented, gelatin liquefied, from thrush. Z. albicans. 



Sugars not fermented, gelatin not liquefied. 



No acid on any sugar. Z. bonaerense. 



Acid in sucrose. Z. album. 



No acid in sucrose. Z. bucale. 



Producing pellicle on liquid media. 



Glucose, maltose, and sucrose fermented. Z. Crust. 



Sugars not fermented, gelatin not liquefied. Z. Alvarezsotoi. 



