242 MEIDICAL MYCOLOGY 



Isolated from a case of macroglossia. Tongue enlarged, occasionally pain- 

 ful, without the usual verrucoid patches of blastomycosis. 



Cells ovoid, 4-5/^ in diameter, gram-positive, not acid-fast. 



On ordinary agar and glucose agar, growth good, smooth, white. A little 

 mycelium in liquid cultures. No fermentation of any sugar-peptone medium. 

 Sometimes a slight acidity is produced with glucose. No change in litmus milk. 

 Serum and gelatin not liquefied. 



Parendomyces Hessleris (Rettger) Dodge, n. comb. 



Blastomyces Hessleris Rettger, Centralbl. Bakt. I, 36: 519-527, 2 pis., 1904. 



Cryptococcus Hessleri Castellani & Chalmers, Man. Trop. Med. ed. 2, 771, 

 1913. 



Torulopsis Hessleri Almeida, Annaes Fac. Med. Sao Paulo 9: 10, 1933. 



Isolated from papules which slowly developed into abscesses following a 

 cut while shaving. Pathogenic to rabbits, white mice, and guinea pigs [case 

 of Hessler, 1898]. 



Cells spherical or slightly ovoid, 6-6.5/x, in malt extract becoming 9-lOju,. In 

 animal tissue cells form mycelium ; cells often sprout as many as 7-8 daughter 

 cells, mostly in a group at one end of the parent cell. No capsule or asco- 

 spores noted. Hessler (1898) noted mycelium but did not describe its mor- 

 phology. 



On agar, colonies white, opaque, circular. On gelatin, colonies small, 

 white, circular, slightly elevated. In blood serum colonies light cream color. 

 On potato, colony light cream color, texture cheesy. On beet, colonies coarsely 

 granular, growth better. In broth, a fine sediment, liquid clear, no pellicle, 

 hyphae occasionally seen. In malt extract, sediment heavy, grayish white 

 with a thin grayish pellicle. No acid or fermentation with sugars. No action 

 on milk. No liquefaction of gelatin. 



Syringospora inexorabilis (]\Iazza & Palamedi) Dodge, n. comb. 



Monilia inexorabilis Mazza & Palamedi, Reunion Soc. Argentina Patol. Reg. 

 del Norte en Tucuman 7: 424-467, 1 pi., 50 figs., 1932. 



Mycotorula Candida Talice & Mackinnon, Reunion Soc. Argentina Patol. 

 Reg. del Norte en Santiago del Estero 8: 165, 166, 1933. 



Lesion began in the commissural surface of the lips, edematous, spreading 

 to the gingival mucosa, tongue, and interior of the mouth generally, producing 

 ulcers. Thence it spread to the lungs (x-ray) the organism being isolated from 

 sputum. Ulcers then appeared on the arms and foot. The disease proved 

 fatal, autopsy showing the lungs to be the principal internal focus of infection. 



Yeast cells in tissues and pus spherical, somewhat suggesting the picture 

 with Zymonema dermatitidis. Yeast cells predominate in cultures, but hyphae 

 seen in potato decoction and serum. 



On Sabouraud glucose, colony white, creamy, slightly drier at the periph- 

 ery, margin festooned, only yeast cells seen in the first 22 days. On simple 

 agar and 3% glycerol agar, potato and potato-glycerol, growth similar but some 

 hyphae noted in 14 days at 37° C. On liquid media, broth remains clear with 



