266 MEDICAL MYCOLOGY 



Parasaccharomyces Sambergeri Beurmaim & Gougerot, Tribune Med. 42: 

 502, 1909. 



Pseudosaccharomyces Busse Samberger, ISbornik Klinicky 5: 466-485, PI. 

 6, 1904. 



Isolated from a lesion which started as a vesicle, then a pustule on the 

 left nostril accompanied by pruritus and spread by scratching. The central 

 area a scar covered with fine scales, caused by the peeling of the horny layer. 

 Around this scar is an ulcerous area with the margin elevated, light red. In 

 this area are small pustules, and the crust is thick, uniform, confluent, cover- 

 ing the whole. Pathogenic for mice. 



In pus, cells spherical or ovoid, thick-walled, yellowish, often in pairs, 

 occasionally showing sprouting. In cultures, cells ellipsoid, thick-walled, with 

 long straight or slightly curved hyphae, cells 10-12/i,. 



On Zopf medium [water 1,000 e.c, ammonium tartrate 10 gm., dihydrogen 

 potassium phosphate 5 gm., magnesium sulphate 2.5 gm., calcium phosphate 

 0.5 gm., peptone 10 gm., sucrose 140 gm.], colony thick, bluish gray, margin 

 shining, even, opaque. On potato, surface rough, verrucose, gray or tan gray. 

 In gelatin stab, colony like a large nailhead with only slight growth along the 

 stab. On liquid media, a ring with aerial hyphae in 3 weeks. Gelatin liquefied 

 in 3 weeks ; glucose fermented. 



Parasaccharomyces oosporoides (Zach) Dodge, n. comb. 



Blastodendrion oosporoides Zach in Wolfram & Zach, Arch. Derm. Syphilis 

 169: 102, 103, 1933. 



Isolated from a case of onychomycosis. Perhaps the organism of Mackin- 

 non (1934), Geotrichoides strain 464, belongs here. 



Cells ovoid, rarely spherical, thick-walled, with a large vacuole and 1-2 

 oil globules, 6.5/x in diameter, ovoid cells 5-6.5 x 7.5-9.7/1.. Sprouting at both 

 ends or irregular, after 3 months forming long branched hyphae with occa- 

 sional blastospores at the septa. Hyphal cells elongate, ends rounded, blasto- 

 spores shorter ellipsoid, not lacrimiform. 



On agar, colony whitish, dull, surface and margin smooth, later becoming 

 yellowish and margin less regular and wavy. On gelatin, colony grayish, dull, 

 margin smooth at first, later wavy, sinking into the gelatin. On gelatin, stab 

 growth superficial with some colonies along the stab. On potato, colony thick, 

 grayish yellow, dull. On carrot, colony white, moist. On maltose broth and 

 autolyzed yeast floccose sediment, no cloudiness and no pellicle. Glucose and 

 fructose fermented. Gelatin liquefied on the ninth day. 



The following two unnamed species of imperfect fungi may possibly be 

 referred to P. oosporoides but present some minor differences. The first agrees 

 rather closely with Zach's description, while the second seems deserving of 

 varietal rank. It is to be hoped that a sufficient number of strains of this 

 organism may be studied to give us more information on variation. This 

 species should also be compared with Mycocandida onychophila (p. 294). 

 [Monilia sp.] Diibendorfer, Derm. Centralbl. 7: 290-302, 3 figs., 1904. 



