214 MEDICAL MYCOLOGY 



Color seems to vaiy with medium, being yellow ochraceous on carrot, rose on 

 beet, and whitish, turning ochraceous, on gelatin. On coagulated serum a thick 

 white colony forms. In vegetable decoctions with sugar, a whitish pellicle and 

 a white sediment form. Acid media less favorable than neutral or slightly 

 alkaline. Gelatin not liquefied. 



Proteomyces Griewanki (Neveu-Lemaire) Dodge, n. comb. 



Mycoderma sp. (sensu Verdun) Griewanki & Laveau, Bull. Soc. Path. Exot. 

 12: 478-482, 1919. 



Mycoderma Griewanki Neveu-Lemaire, Precis Parasitol. 70, 1921. 



First lesion appeared as tumor at base of big toe. In the course of five 

 years extended dorsally and internally in foot, which finally became globose 

 and like a bear's paw. Ulcerous, but was painful only on pressure, not sensi- 

 tive to pricking. Finally the foot was amputated. A study of the tissues dis- 

 closed red grains. 



Yeast cells 4-6/a in diameter, end to end, yellow brownish with numerous 

 rounded, cocciform spores in chains or clusters. Filaments long, flexuous, sep- 

 tate, white, refractive, 2-2.5//, x 15/a, sometimes piled up, curved, or branched. 

 Blastospores rounded, arranged in lines. Chlamydospores usually intercalary, 

 rarely terminal. Arthrospores cut off squarely. Staining by Ziehl method 

 good. By Gram method, walls stained, some cells staining deeply. Proto- 

 plasm granular, chlamydospores, arthrospores and budding elements rose. 

 Some arranged in spirals and helices. 



Cultivated on straw infusion (1.5% agar), on banana, potato + glycerol, 

 and Sabouraud maltose agar, the latter one being unsuccessful. On the former 

 in six days appear small cerebroid masses, gelatinous, yellowish, becoming size 

 of small pea. Finally a rose-colored efflorescence over surface of media. 



Proteomyces Faverae Dodge, n. sp. 



Oidium sp. Favera, Giorn. Ital. Mai. Ven. Pelle 55: 650-729, 10 pis., 1914. 



On man produces cutaneous ulcers similar to those of Z. dermatitidis. Path- 

 ogenic to laboratory animals. 



In 5-day-old cultures, the cells are spherical, 2-30/* in diameter, thick -walled, 

 sprouting. Hyphae slender, straight or slightly curved, homogeneous, usually 

 1-2 sprouting from each sprout cell; septa not visible, terminal cell swollen. 

 After 15 days, hyphae are septate, branched, unequal ; yeast cells elongate in 

 chains of 5-8 cells. Four-to-six-week-old cultures show only septate hyphae of 

 long cylindric cells and chlamydospores ; chains of ovoid spores 2-3 cells long 

 on lateral branches. 



Optimum growth at 34°-38° C, growth very slow at 18°-20° C. On 

 Sabouraud glucose agar, colony is thick, yellowish, white, humid, creamy, 

 margin festooned, surface irregular, rugose becoming cerebriform. After 2 

 weeks, shining white mycelium develops which rapidly covers the yeast colony 

 and spreads beyond it, suggesting the pleomorphism of the Trichophytoneae. 

 The colony becomes folded and furrowed with the bottom of the furrows moist 

 and yollowish. On Sabouraud maltose, colony is similar, but with a slight rose 

 tint. On common agar, thick, whitish, moist and rugose, mycelium very slow 



