252 MEDICAL MYCOLOGY 



Obtained in pure culture on 5% citric acid agar. Grows well on Sabour- 

 aud agar. Growth poor on potato and potato glycerol. On acid potato, 

 colonies thick, creamy, confluent. Growth on carrot similar to that on acid 

 potato but less. On beet, still less. Organism will grow in 1.5% NaOH 

 glycerol peptone. In liquid media, there is abundant growth at bottom. In 

 malt extract, a ring in 48 hours. In prune decoction, broth, or liver broth, 

 Hay en, Hansen, or Cohn's solutions, growth is good: in carrot decoction, poor. 

 Also poor in Pasteur, Laurent, or Nageli's solutions. Glucose and fructose 

 fermented. Lactose, galactose, mannitol, sucrose, and maltose not fermented. 

 Gelatin not liqueJSed. 



Castellania londinensis (Castellani & Chalmers) Dodge, n. comb. 



Monilm londinensis, Castellani & Chalmers, Man. Trop. Med. ed. 3, 1084, 

 1919. 



Mycelohlastanon londinense Ota, Jap. Jour. Derm. Urol. 28: [4], 1928. 



Isolated from a case of thrush, also found in the vagina. 



Colony white. Acid formation and fermentation with glucose and fruc- 

 tose ; acid only with maltose, galactose, sucrose, and lactose. Milk acidified 

 and clotted. 



Castellania Copellii (Neveu-Lemaire) Dodge, n. comb. 



Cryptococcus sp. Copelli, Giorn. Ital. Mai. Ven. Pelle 46: 467-492, 2 pis., 

 1912. 



Cryptococcus Copellii Neveu-Lemaire, Precis Parasitol. Hum. 79, 1921 ; Ota, 

 Ann. Parasitol. Hum. Comp. 2: 51-53, Fig. 6, 1924. 



Hefe Copelli Sasakawa, Centralbl. Bakt. I, 88: 269-285, 1 pi., 1924. 



Mycelohlastanon Copellii Ota, Jap. Jour. Derai. Urol. 28: [4], 1928. 



Torulopsis Copellii Almeida, Annaes Fac. Med. Sao Paulo 9: 10, 1933. 



Referred to Cryptococcus Breweri by Vuillemin, Champ. Parasit. Homme 

 Anim. 96, 1931. 



Isolated from lesions on the tongue. Pathogenic to rabbits and guinea 

 pigs. 



Cells spherical, sparingly allantoid, 5-12/^ in diameter in tissues, 3-16yu, in 

 cultures. Elongate cells in older cultures. Beginnings of hyphal formation 

 was observed on certain media, but they Avere not studied long enough to 

 obtain spores. Optimum temperature for growth 33°-38° C. ; no growth at 

 42°-45° C. 



Colonies small, white, rounded, elevated at center. On Sabouraud agar, 

 colony circular, crateriform, yellowish white, moist, opaque. On potato, 

 colony thick, an elevated plateau, with margins coarsely festooned, opaque, 

 velvety. On beet, colony similar but rose color. On gelatin, colony shining, 

 glassy white, round, elevated, margin regular. Growth strictly aerobic. On 

 coagulated serum, colony thin, dry, powdery. On liquid media, no pellicle, 

 slight turbidity, abundant sediment of tiny white flocci (glucose, mannite, 

 maltose-peptone, wine, milk, Raulin's solution). Growth on urine or on horse 



