SACCHAROMYCETACEAE 809 



No ring or pelliclo on malt cxtruct, sodinKMit brownish white, sucrose inverted. 



D. Leopoldi. 



D. Lundsgaardi. 



D. Laedcgaardi. 



D. Hildegaardi. 

 Pellicle on malt extract, sucrose inverted. D. G^Ulliermondi. 



Fermentation unknown, probably close to D. Fahryi. D. Burnirri. 



In the following descriptions I have tried, to translate and bring together 

 the salient points of each organism nnder the original name. Ota's descriptions 

 of numerous new species seem to have been too hurriedly written without a 

 sufficient background to appreciate the stability of characters and with too 

 little biometric data to give much validity to his cell measurements. Since 

 most of the cultures had been isolated many years previous to his studies and 

 been carried in stock cultures for so long, it is possible that they may not be 

 the original organism isolated from the cases mentioned. Quite probably 

 Dekker is right in referring most of his species to D. Matruchoti. On the other 

 hand, it seems strange that a single species of yeast should produce such dif- 

 ferent types of lesions as Ota's A'arious species have been reported to do. 



Debaryomyces Hudeloi (Gougerot) Fonseca, Brasil Med. 36: 101-102, 1922. 



Cryptococcus sp. Hudelo, Duval & Laederich, Bull. Mem. Soc. Med. Hop. 

 Paris 23: 723-734, 1906. 



Atelosaccharoniyces sp. Duval & Laederich, Arch, de Parasitol. 14: 224- 

 318, 1911. 



Atelosaccharomyces Hudeli Gougerot, Paris Med. 1: 462, 1911. 



Debaryomyces KloecJieri var. Hudeloi Dekker, Verhandel. K. Akad. Wet- 

 ensch. Amsterdam Afd. Natuurk. 28: 473, 1931. 



Isolated from blastomycosis with multiple foci, clinically more or less 

 similar to that produced by Atelosaccharomyces hominis. 



Pathogenic for mice, less so for rats and guinea pigs, not for rabbits, dogs, 

 or hens; subcutaneous inoculation in guinea pig produced abcesses, which 

 healed spontaneously in a fortnight. 



Cells usually spherical, occasionally ellipsoid, isolated or in pairs, very 

 rarely in short chains of 4-5 cells, mostly 2-4/* in diameter, with ellipsoid cells 

 up to 8/* and giant cells 16 x 6/x [original description states cells 2-20/*] mostly 

 uniguttulate (Fig. 64, 1-3). Copulation heterogamous, asci 1-spored, asco- 

 spores 2-3^ in diameter, sparingly echinulate with a large fat globule (Fig. 

 64,4). 



Optimum temperature 22° C, growth very good at 38° C, not anaerobic. 

 Ota reports that after 18 years oplnnum temperature is 30°, growth poor at 

 37°, good at 12° C. 



On Sabouraud glucose agar, colonies opaque, smooth, moist, shining, 

 margin regular becoming undulate, consistency mucous, viscid, strongly ad- 

 herent to the agar but not penetrating it, 1.5 mm. thick, creamy, growth not 

 spreading, finally becoming yellow bister, then cafe-au-lait, and deep brown 



