334 MEDICAL MYCOLOGY 



Colonies on blood agar very small, white, punctiform, moist, by transfer 

 gradually accustomed to all the usual media. On malt (mizuame) agar, colo- 

 nies moist, white, round, opaque, finally confluent and yellow, especially at 

 room temperature. GroAvth poorer on ordinary agar, blood, glycerol, and 

 ascites agar. On potato, colony moist, white, confluent. On broth and pep- 

 tone solution, no pellicle, sliglitly granular sediment. On malt extract and 

 sugar solutions, a ring develops, also turbidity and a yellowish white sediment. 

 No fermentation ; acid in arabinose, xylose, glucose, fructose, galactose, man- 

 nose, sucrose, lactose, maltose, raffinose, inulin, starch, dextrin, mannite, and 

 erythrite. Milk coagulated in 10 days. Gelatin not liquefied in several weeks. 



Cryptococcus hondurianus (Castellani) Dodge, n. comb. 



Torulopsis hominis var. Jwnduriana Castellani, Med. Press Circular 136: 

 438-443, 1933; Jour. Trop. Med. Hyg. 36: 311, Fig. 36, 1933. 



Torulopsis neoformans Lodder, Anaskosporogenen Hefen 1: 176-178, 1934. 



Isolated from blastomycosis of the skin with pulmonary complications in 

 Honduras. 



Cells spherical, 3.5-10. 5ja, occasionally ovoid. In malt extract, cells 3.9-5 

 X 4.5-5.5/i,. 



On glucose agar, colony smooth, mucoid, yellowish. No pigmentation of 

 mannitol agar. On malt agar, colony yellowish, humid, smooth, slimy, margin 

 smooth. On malt gelatin, colony dull, almost smooth, margin smooth. On 

 malt extract, broad yellowish ring, well-developed sediment, and a few slimy 

 floating islets. No fermentation and no acidity with carbohydrates except 

 glucose, sucrose, xylose (and in one strain on glycerol). Serum not liquefied; 

 gelatin liquefied very slowly after 2 weeks in one strain, in other not liquefied. 



Cryptococcus cong-lobatus (Redaelli) Pollacci & Nannizzi, Miceti Pat. 

 deiruomo e degli Anim. 7: No. 63, 1928. 



Torulopsis conglohata Redaelli, I Miceti come Associazione Microbica nella 

 Tubercolosi Polmonare Cavitaria, 1925. 



Isolated from lungs with much destruction of tissue, in Italy. Later iso- 

 lated by Carnevale-Ricci from tonsillar crypts. Subsequently found in several 

 other cases in lesions of the lung. 



Cells spherical or slightly ovoid, 1.5-3/x, occasionally up to 4.5/^, in diam- 

 eter, at first homogeneous then vacuolate and uniguttulate, solitary or in 

 groups of 3-6 cells ; on carrot, cells somewhat larger, 5-6ju, ; thick-walled chlamy- 

 dospores, 5.5-6.5/*, present in old cultures but no mycelium. Chlamydospore 

 wall rupturing on germination. No ascospores. 



On Pollacci agar, colony thick, luxuriant, spreading, white, smooth, shin- 

 ing, margin smooth. Colonies on Sabouraud agar similar. On carrot agar, 

 colony white, creamy, opaque, margin smooth or slightly striate. On Gorod- 

 kova agar, colony brown, opaque, easily separable from the substrate. On 

 carrot, colony creamy. Avhite, margins irregularly lobed. On potato, colony 

 grayish, surface slightly irregular, thick and opaque, small. On malt gelatin, 

 colony plane, yellowish, opaque, 3 cm. in diameter in 30 days, margin finely 



