SACCHAROMYCETACEAE IMPERFECTAE 335 



and irregularly dentellated. On malt extract, producing fragments of a milky 

 white ring with traces of a pellicle floating on the liquid, with dirty yellow 

 sediment. Milk coagulated. 



Cryptococcus Kleini (Weis) Colin apud Gueguen, Champ. Paras. Homme 

 114-115, 1904. 



Torula sp. Klein, Jour. Ilyg. 1: 90-94, 1901. 



Torula Klein Weis, Jour. Med. Res. 7: 280-311, Pis. 21-24, 1901. 



Isolated from milk along with other organisms. Pathogenic for guinea 

 pig, rabbit, and dog, producing tumor in guinea pig in original case. 



Cells spherical, 2-8/* in diameter, homogeneous in content, finely granular, 

 thin-walled when young, finally surrounded with a hyaline capsule occupying 

 about one-fourth the total diameter. On solid media cells secrete a mucinous 

 sheath. Growth from 20° to 37° C. 



On glycerol, malt, and sugar agars, colonies thick, viscid, yellowish. Colo- 

 nies on nutrient agar remain white. On alkaline nutrient gelatin, colony 

 thick, rounded, moist, center raised, white in reflected light, brown and granu- 

 lar in transmitted light. On sugar gelatin, growth more rapid, colony light 

 yelloAv. After 5-6 weeks, gelatin slowly liquefied into a thick, turbid, syrupy 

 mass. On blood serum, colony white gradually becoming yellowish, slimy, 

 growth very slow. On potato, colony yellowish, surface convoluted, margins ir- 

 regular. On malt extract, pellicle delicate, sediment flocculent to granular, ring 

 well developed. In glucose broth, a slight pellicle and a powdery white sedi- 

 ment appear, the liquid remains clear. Growth on milk good, medium not 

 coagulated. No fermentation of lactose, sucrose, maltose, or glucose. 



Cryptococcus Guilliermondi Beauverie & Lesieur [name with reference to 

 previous description]. Jour. Physiol. Path. Gen. 14: 998, PI. 11, 1912. 



Levure Guilliermond & Lesieur, C. R. Soc. Biol. 70 : 952-954, 1911. 



Isolated from the lungs of a man dying with cancer of the kidney. Lung 

 symptoms resembled tuberculosis without accompanying fever. Inoculations 

 into guinea pig negative. 



Cells spherical or ovoid, 3-5 x 2.8-4.3/x, solitary or in pairs, with a thick 

 membrane but no capsule, possessing one or two vacuoles and numerous oil 

 droplets. In fruit juices, cells 3.5-6.4/j, in diameter, even larger in Raulin solu- 

 tion. In old cultures elongate cells may be seen. Sometimes, though rarely, 

 these are branched. Giant cells common. No spores found in cultures on 

 plaster blocks, Gorodkova agar, or slices of caiTot. 



On carrot, growth abundant, white even in old cultures, viscid. On 

 potato, growth feeble, colonies size of pinhead, white, dry. On agars, grape 

 juice, broth, peptone solution, growth is good, with viscid, yellow colonies ; 

 grayish in age. In other fruit juices, growth poor, sediment produced but no 

 pellicle. Sugars are inverted, but there is no alcoholic fennentation. 



Crjrptococcus psicrofilicus Nino in Speroni, Llambias, Parodi & Nino, Bol. 

 Inst. Clin. Quiriirg. Univ. Buenos Aires 5: 94-155, 35 figs., 1930. 



Isolated from a nodulo-ulcero-scabrous dermatitis originally, with subse- 

 quent involvement of the prostate, gastritis, and meningoencephalitis, this 



