SACCHABOMYCETACEAE IMPERFECTAE 337 



Isolated from pus of an inguinal abscess with symptoms of gonococcemia in 

 a negro woman, but all attempts to isolate Neisseria go7iorrhoeae were unsuc- 

 cessful. Highly pathogenic for guinea pigs and rabbits. 



Yeast cells in pus 7-15/* in diameter, spherical or ovoid, walls thick, en- 

 veloped in a capsule. Gram-negative or nearly so, not acid-fast. Each cell 

 with 1-5 spherical refractile granules. In cultures, morphology similar to that 

 in pus, the gelified matrix appearing only in old cultures and holding the 

 individual cells together in short chains. No ascospores. 



On Sabouraud agar, colonies in 24 hours small, white, opalescent, round, 

 becoming coarsely granular and hemispheric, then thickly mucoid and heaped 

 up in the center, finally confluent and of varying shades of yellow and brown. 

 On blood agar, colonies sparse, discrete, small, grayish white. On Loffler's 

 blood serum, colonies similar but smaller and more watery. In broth, growth 

 poor, forming a thick adherent sediment with a tendency to grow up the sides 

 of the tube. No fermentation of sugars, no liquefaction of gelatin, no action 

 on milk, no indol formation. 



Crjrptococcus histolyticus Stoddard & Cutler, apud Castellani Amer. Jour. 

 Trop. Med. 8: 393, 1928. 



Torula sp. Frothingham, Jour. Med. Res. 8: 31-42, Pis. 3-4, 1902; Tiirck, 

 Deutsch. Arch. Klin. Med. 90 : 335-366, 1907. 



Torula histolytica Stoddard & Cutler, Monog. Rockefeller Inst. Med. Res. 

 6: 1-98, 9 pis., 1916; Ota, Ann. Parasitol. Hum. Comp. 2: 41-43, 1924. 



Torulopsis histolytica Castellani & Jacono, Jour. Trop. Med. Hyg. 33: 316, 

 Fig. 44, 1933. 



Isolated from the lung of a horse by Frothingham (1902). Experimental 

 inoculation by Stoddard & Cutler (1916) produced brain lesions similar to 

 those in human brains caused by C. meningitidis. Perhaps organism of Voss 

 (1923) should be referred here. 



Cells spherical, 1-6/* in diameter (average 3-4/*), sprouting from the 

 medium-sized cells. Capsule 0.5-1.0/i thick. No spores observed. 



On glucose agar, colonies at first white, then more or less yellowish, 

 heaped up, smooth, pasty, shining, thick. In broth, slight turbidity, no pellicle, 

 fine white sediment. No fermentation of lactose, sucrose, dextrin, or glucose. 

 No liquefaction of gelatin. 



Doubtful Species 



The following species of pathogenic yeasts have been too poorly described 

 to place definitely. 



Cryptococcus Breweri (Verdun) Castellani & Chalmers, Man. Trop. Med. 

 ed. 2, 771, 1913. 



Blastomyces sp. Brewer & Wood, Ann. Surgei-y 48: 889-896, Pis. 1-7, 1908. 



Atelosaccharomyces Breweri Verdun, Precis Parasitol. 1912; Froilano de 

 Mello, Paes & Sousa, Arq. Hig. Pat. Exot. 6: 34, 1918. 



