SACCHAROMYCETACEAE IM PERFECT AE 341 



On agar, colony thin, grayish white, slimy. On potato, a grayish white, 

 thick membrane appears. Membrane consistency of "mizuame, " with fine 

 hyphae. Peptone solution, with or without sugar, remained clear. No acid 

 or gas formed in presence of sugars, but alcohol was detected by iodoform test. 



Perhaps this was the strain later sent to the Centraalbureau voor Schim- 

 melcultures under the name Cryptococcus hominis and referred by Lodder 

 (1934) as C. neoformans. 



Cryptococcus sp. 



Blastomyces sp. Escomel, Bull. Soc. Path. Exot. 8: 90-92, 1915. 



Isolated along with Leishmania in the disease called "espundia" in Peru. 

 Started as cutaneous ulcers on neck and limbs and persisted for a long time. 

 Secondary lesions, nodular ulcers suggesting a mulberry, develop in mucus 

 of nose, pharynx, tonsils, pillars of fauces, soft palate, tongue, cheeks, gums, 

 larynx, and sometimes even extend to the external surface of the head. The 

 ulcers gradually extend, accompanied by great salivation, ending after 20-30 

 years in a cachectic state. The disease appears somewhat analogous to that 

 in Brazil described by Splendore & Lutz. 



Cells ovoid, rarely spherical, 1.9-8/t in diameter, with granules staining 

 purple with Giemsa stain while protoplasm stains blue. Cells solitary or in 

 pairs, reproducing by sprouting. 



Organism grows well on Sabouraud media, glucose and sucrose solutions, 

 milk, potato, carrot, Arracacha esculenta, Ipomoea datatis and Oxalis tuherosa. 



Cryptococcus sp. Irons & Graham, Trans. Chicago Path. Soc. 6: 445-448, 

 1906; Jour. Infect. Dis. 3: 666-682, 1906. 



Coccidioides immitis strain 2 Hamburger, Jour. Infect. Dis. 4: 201-209, 

 1907. 



The characters as given by Irons & Graham show a close similarity to 

 the mycelium of Zymonema capsulatum and not to Coccidioides. Hamburger 

 does not figure his strain. 



PSEUDOSACCHAROMYCES 



Pseudosaccharomyces van Laer, Bull. Ass. Beige Chimistes No. 3, 1893 ; 

 Klocker, Centralbl. Bakt. II, 35: 375-388, 1912, not Samberger, Sbornik Klini- 

 cky 5: 466-485, PI. 6, 1904, nor Briosi & Fameti, Atti 1st. Bot. R. Univ. Pavia 

 II, 10: 31, 1906. 



Eansenia Zikes, Centralbl. Bakt. II, 30: 145-149, 1911, not Zopf, Zeitschr. 

 Naturw. 56: 539, 1883, nor Lindner, Jahrb. Vers. Lehranstalt Brau. Berlin 

 7: 448, 1904. 



Kloeckeria Janke, Centralbl. Bakt. II, 69: 310, 1923 (spelling corrected to 

 Kloeckera by Janke, Centralbl. Bakt. II, 76: 161, 1929). 



I have been unable to locate a copy of van Laer's publication and 

 hence I am not sure as to the synonymy of Haiisenia Zikes and Kloeckera 

 Janke. The type species of the two latter is Saccharomyces apiculatus Reess 



