ENDOMYCETALES 



135 



slower, gelatin liquefied in 13-15 days. On broth, grayish white pellicle settling 

 after 6-7 days and replaced by another pellicle. 



From the brief description, the systematic position of this organism is 

 uncertain. Many characters suggest much closer relation to the Favotricho- 

 phyfon ochraceuni group rather than to the yeasts (near Mycotornla) . Clini- 

 cally it seems very close to the European T. Beigeli, if it be not the same 

 organism. 



Trichosporum ovcides Behrend, Berliner Klin. Woch. 27: 464-467, ld90. 



Trichosporum ovale Unna ap. Vuillemin, Arch, de Parasitol. 5: 38-66, 12 

 figs., 1902. 



ITrichosporum giganteum. Unna, Deutsch. Med. Zeitschr. 1895: 255-256, 

 1895, non Vuillemin 1902. 



Isolated from sycosis in Germany, forming brownish yellow nodes on the 

 hair, leaving the hair shaft nearly intact. 



Spores ovoid, 2-4.5 x 1-4/x, sometimes in-egular. 



Colonies cerebriform, blackish brown on several media. 



Trachsler (1896) tried to separate T. ovoides and T. giganteum, but the 

 differences between the strains are so slight that they are probably not sig- 

 nificant. 



Trichosporum glycophile DuBois, Ann. Derm. Syphiligr. V, 1: 447-456, 

 1910. 



Causing irritation in female genitalia. The hairs which have been moistened 

 with urine (patient was a mild diabetic) have nodosities and terminate in 

 brushlike tips, often breaking a few millimeters from the skin. The mycelium 

 proliferates between the fibrillae of the hair and terminates at the surface 

 under a layer of sporiform elements. Not pathogenic for the guinea pig, 

 rabbit, or rat. 



The following description of morphology based on cultures from 5% 

 maltose agar, 5% peptone agar, or 2.5% maltose + 2.5% peptone agar. The 

 yeast cells 5-6/x in diameter. The hyphae slender, septate, at long intervals, 

 uniform at least in the terminal portion. As the hyphae become older, they 

 become thicker, more tortuous, and end in a terminal swelling. Spores 

 verticillate, regularly spaced. Chlamydospores large. 



On solid sugar media, abundant mycelium below the surface while on 

 the surface a small gray colony scarcely covers the hair. On solid protein 

 media, colonies yellowish, smooth, humid, proliferating on surface with cen- 

 tral elevation and sometimes Avith little knobs, margin with a circular elevation 

 connected with the center by furrows. Cross inoculations showed these two 

 types of colonies to be the same organism. On Sabouraud agar, colonies smooth 

 gray, or yellowish, growth rapid. On broth agar and peptone agar, yeast 

 form prevails on the surface, growth slow, colony gray, smooth with a slight 

 central knob, colony bordered by fine hyphae at the end of 3 weeks. On liquid 

 media, grayish white pellicle, dry but not poAvdery, pellicle settling in 10-12 

 days and a new one forms. On potato, colonies gray yellowish, moist, rugose. 



