SACCHAROMYCETACEAE IMPERFECTAE 345 



Producing pharyngolaryngitis. Symptoms are a tickling sensation in 

 throat, burning sensation in air passages, continual cough with abundant ex- 

 pectoration. Free edge of epiglottis and upper face of arytenoid cartilage 

 had principal lesions which appeared as large, protruding, opaline plaques 

 separated by narrow bands of healthy tissue. No lesions in larynx. No 

 tuberculosis or syphilis. Lesions finally cured by medication with potassium 

 iodide. 



Cells 4-8/i in diameter ; ascospores not seen. On carrot, optimum tempera- 

 ture for growth was 28°-32° C, growth ceases at 39°-40°, but colony lived 

 for 15 days at least at this temperature. Pellicle on broth at 25°-28° and 32°, 

 but not at 35°-37°. 



On agar and gelatin plates, colonies round and white. On potato, colo- 

 nies white, turning gray later. On carrot, colonies white, smooth, humid. On 

 gelatin stab, growth in depths as well as at surface. Pellicle in broth. In 

 sugar broths, growth is active, with the production of a uniform cloudiness. 

 Glucose and maltose fermented, but not lactose or galactose. Sucrose is in- 

 verted. Milk coagulated on twelfth day but casein not peptonized. Gelatin 

 not liquefied. 



Atelosaccharomyces clericus Dodge, n. sp. 



Cryptococcus sp. Clerc & Sartory, C. R. Soc. Biol. 64: 135-137, 1908. 



Isolated from a case of chronic angina with small yellowish concretions 

 on pillars of fauces, tonsils, and posterior wall of pharynx. Pathogenic to 

 guinea pig. 



Cells ovoid, 7-10 x 5/a, isolated or in groups of five or six, sprouting at 

 one pole. No mycelium or spores on any medium tried. Gram-positive. 

 Optimum temperature 30° C. 



Colony on agar white, on potato dirty white. On carrot, colony at first 

 smooth and pure white, later becoming granular, pulverulent, and pale rose 

 in color. Poor growth on serum. Alcoholic fermentation of sucrose and 

 maltose but not galactose. No aldehyde formation. Sucrose inverted. Starch 

 not digested. Gelatin not liquefied, milk coagulated but no digestion of curd. 



Atelosaccharomyces pyogenes (Mattlet) Dodge, n. comb. 



Cryptococcus pyogenes Mattlet, Ann. Soc. Beige Med. Trop. 6: 13-14, 1926. 



On potato decoction, at 37° C, appear yeast forms, spherical, rarely ovoid, 

 6-9/* in diameter, multiplying only by sprouting. No fat granules. 



On Sabouraud agar, colonies circular, dull, slightly yellowish at the center 

 and crumpling with fine radial striations, giving the margin a lacy appearance. 

 On potato decoction, there is formed a coherent, membranous sediment Avhich 

 breaks up on shaking. Acid formation and very active fermentation with 

 glucose, fructose, maltose, galactose, and sucrose. No action on gelatin or 

 milk. 



This organism is close to Cryptococcus hominis Vuillemin, but differs in 

 its active fermentive power. 



