346 MEDICAL MYCOLOGY 



Perhaps the unnamed species of Cryptococcus described by Brazzola be- 

 longs here. 



Cryptococcus sp. Brazzola, Mem. K. Accad. Sci. Bologna V, 6: 303-310, 

 1 pi., 1897 (Sez. Med. Chirurg. 43-50). 



Isolated from a case of gangrenous pharyngitis with infiltration of all 

 the glands of the neck. Pathogenic to guinea pigs. 



Cells of variable size and irregular groupings, walls thick. 



On agar, glycerol agar, and gelatin, colonies round, margins slightly 

 fimbriate, center thicker, yellowish white, becoming darker on aging. On 

 potato, growth rapid, colony thick, mammillate, margin fimbriate, pearl white 

 becoming dark yellowish, especially after exposure to rather intense light. 

 On broth, a slight pellicle and no turbidity. On milk, growth luxurious with- 

 out coagulation. Fermentation of glucose, maltose, and lactose. Optimum 

 temperature between 30° and 35° C. 



Doubtful Position 



Atelosaccharomyces Gottii (Neveu-Lemaire) Froilano de Mello, Paes & 

 Sousa, Arq. Hig. Pat. Exot. 6: 34, 1918. 



Cryptococcus sp. Gotti & Brazzola, Mem. R. Accad. Sci. Bologna V, 6: 

 721-754, 2 ph., 1897 [Sez. Med. Chirurg. 257-290]. 



Atelosaccharomyces sp. Beurmann & Gougerot, Bull. Mem. Soc. Med. Hop. 

 Paris III, 28: 251, 1909. 



Isolated from lesions in tJie nasal passages of a horse. Pathogenic for 

 guinea pigs. 



Cells from the lesion encapsulated, large, slightly ovoid or spherical, 

 sprouting. In cultures capsule absent or slightly developed. 



On glycerol agar, white to mother-of-pearl colonies, creamy to almost 

 gelatinous, margins slightly fringed, browning in age. On potato, growth 

 rather rapid, colony rather thick, creamy, at first white, then grayish and 

 finally gray brown, or even tobacco brown if exposed to light. On gelatin, 

 colonies mother-of-pearl white, margins fringed, becoming granular and ir- 

 regular, yellowish gray but not brown. No growth on coagulated serum. 

 Growth poor on liquid media, no turbidity and no pellicle, with a slight sedi- 

 ment at the bottom of the tube. Gelatin not liquefied. 



The position of this species is uncertain since no fermentation is recorded, 

 and it is quite likely it belongs in Cryptococcus or even in Zymonema, since 

 it was not observed long enough to be sure that no hyphae were produced. 

 Sprouting occurs only at the ends of the cells, and occasionally the cells cling 

 together in short chains. 



Cryptococcus niger (Mafucci & Sirleo) Gedoelst, Champ. Paras. Homme 

 59, 1902. 



Saccharomyces niger Mafucci & Sirleo, Policlinico, Sez. Chirurg. 2: 138- 

 144, 245-254, 1895. 



Torulopsis niger Almeida, Annaes Fac. Med. Sao Paulo 9: 10, 1933. 



