352 MEDICAL MYCOLOGY 



Cells ellipsoid, 3-4.5 x 5-7/u,, mostly single or in pairs, rarely in small chains. 



On malt agar, colony red with orange tone, moist, smooth, slimy. On malt 

 gelatin, colony shining, rose, punctate, margin dentate. On malt extract, 

 slimy islets, a broad ring, with thick slimy sediment, liquid turbid, rose color. 

 No fermentation ; acid with glucose, fructose, and mannose ; potassium nitrate 

 assimilated ; gelatin liquefied. 



Tonilopsis rubra (Demne) Almeida, Annaes Fac. Med. Sao Paulo 9: 10, 

 1933. 



Saccharomyces ruher Demne, Ann. Microgr. 2: 555, 556, 1889 [1890] ; Mitt. 

 Naturf. Ges. Bern 1889: ix-xi, 1890; Festschr. E. Kenoch Berlin, 1890; Casa- 

 grandi, Ann. Ig. Sperim. 8: 535-545, 1897-1898. 



Cryptococcus ruher Vuillemin, Bull. Seances Soc. Sci. Nancy III, 1: 61, 

 1900. 



Rhodotorula rubra Lodder, Anaskosporogenen Hefen 1: 69, 1934, 



Originally isolated from a red cheese and later from feces of children 

 Avith diarrhea who drank some of the milk from which the cheese was made. 

 Thought by Demne not to be j)athogenic, although when pure cultures were 

 fed to dogs in large doses, digestive disturbances resulted. Casagrandi iso- 

 lated the organism from diabetic urine which had been exposed to the air. 

 Recently Bagnacci (1926) reports this species in glossitis of an infant. Patho- 

 genie in subcutaneous injections to guinea pigs and rabbits, also by ingestion 

 of milk cultures which produce diarrhea. 



Cells 3.8-4.5-6.8/x in diameter, in short chains of 3-4 cells. Chlamydospores 

 7.5-8.5 X 5-5.5/x. 



Grows on glucose agar, better on glycerol agar, producing pale rose colo- 

 nies which become reddish chestnut in color and are elevated, shining, with 

 margin lobed. On Pollacci agar, colony at first whitish becoming red, plane 

 or with center elevated, moist, shining, with margin lobed. On malt agar, 

 colony orange, moist, smooth, margin pellucid. Growth on potato even bet- 

 ter, colony red, 2-3 mm. thick. No growth in agar with more than 5% tartaric 

 acid. On gelatin, colonies yellowish at first becoming clear raspberry red, 

 nailhead size, with whitish lobed margin. In glucose broth, there is a whitish 

 pellicle, reddish sediment, and no turbidity. Casagrandi reports fermentation 

 of glucose and sucrose, others report no fermentation. Sucrose inverted. 

 Milk not acidified or coagulated. Gelatin liquefied in 2-4-10 months. 



Tonilopsis Sanniei Ciferri & Redaelli, Atti 1st. Bot. R. Univ. Pavia III, 2: 

 245-248, 283, 1925. 



Rhodotorula Sannei Lodder, Anaskosporogenen Hefen 1: 99-101, 1934. 



Isolated from lungs. Not pathogenic for laboratory animals. 



Cells ovoid or ellipsoid, often spherical, single, at first hyaline then gut- 

 tulate, 4-5 x 6-7.5ft, no ascospores or mycelium. 



On carrot agar, colonies peach blossom red, margins somewhat serrate, 

 then the surface wrinkled and brick red. On must gelatin, colonies round 

 with fine concentric furrows, blood red. On malt gelatin, colonies moist, 



