478 MEDICAL MYCOLOGY 



seen in the scales from a psoriatic lesion. So far as I have been able to ascer- 

 tain, Sabouraud was the first to nse Epidermophyton as a generic name in its 

 present sense. 



The type species is Epidermophyton inguinale Sabourand or E. floccosum 

 (Harz) Langeron & Milochevitch. 



Growing only in the horny layer of the epidermis, not attacking hair fol- 

 licle or hair, closterospores common and conspicuous in most species, chlamy- 

 dospores less abundant and conspicuous, aleurospores rarely present. Only 

 one species has been carefully studied morphologically and cytologically, two 

 species of Castellani are so poorly described that they can be referred here 

 only on the basis of the lesions caused and may even be synomyms of later 

 but better described species. Two other species of MacCarthy, E. gypseum 

 and E. niveuni, are very close in characters of the giant colony to Ectotrichophy- 

 ton mentagrophytes (T. gypseum) and Ectotnchophyton felineum (T. niveum) 

 respectively and need further study before they are finally classified. 



The remaining species form a compact group of closely allied species and 

 show less degeneration in connection with specialized parasitism than do the 

 other series. 



Key to the Species of Epidermophyton 



Colony white, becoming pale yellowish green, never pink or reddish. 



Closterospores absent. 



Colony white or gray, cerebriform, not velvety, no pleomorphism. 



E. cerebriforme. 



Colony clear white, with concentric elevations and depressions, reverse brownish, long 



fine white velvet, no pleomorphism. E. niveum. 



Colony yellow cream color, with long white velvet; reverse brownish or violaceous, 



pleomorphic in two or three weeks. E. pedis. 



Colony white becoming cafe-au-lait color, with a sliglit central crater with flexuous 



radial furrows, powdery, pleomorphic in five weeks. 



^, ^ E. aypseum. 



Closterospores present. 



Growth rapid, pale buff boss, rest white; on glucose media reverse chestnut brown 

 to almost black with a yellowish margin; inoculable into experimental an- 

 imals, lesion evanescent, aleurospores present; spirals on Sabouraud agar. 



E. interdigitale. 

 Growth slow, greenish yellow, radially furrowed, reverse concolorous; inoculable into 

 experimental animals with great difficulty if at all; aleurospores very rare; 

 spirals only on complex carbohydrate media. E. floccosum. 



Colony some shade of pink, at least when freshly isolated. 

 Colony multizonate, alternating white and purple zones. 



Central umbo white with 20 radial furrows, margin purple, pleomorphism in 65 days, 



pigment diffusing on potato; reverse red brown. E. plurizoni forme. 

 Central crater rose purple without radial furrows, margin yellowish white; no 

 pleomorphism ; pigment not diffusing ; reverse concolorous on sugar media, 

 red brown on peptone. E. lanoroseum. 



Colony not multizonate, never more than three zones. 



Center convex, fire red with a salmon border; growth rapid (7 cm. in 11 days), 

 pleomorphism in 16 days on glucose, slight diffusion of pigment in freshly 

 isolated colony; hard papules, coriaceous; peculiar odor in lesion. 



E. salmoneum. 



